| 芫花药材的HPLC指纹图谱及ESI-MS分析 |
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| 引用本文： | 邓仕任,夏林波,董倩,郭晏华,贾天柱.芫花药材的HPLC指纹图谱及ESI-MS分析[J].中国实验方剂学杂志,2011,17(24):32-35. |
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| 作者姓名： | 邓仕任 夏林波 董倩 郭晏华 贾天柱 |
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| 作者单位： | 辽宁中医药大学药学院,辽宁大连,116600 |
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| 基金项目： | 国家"十一五"科技支撑计划课题 (2006BA109B06-07-1); 辽宁中医药大学药学人才基金 (yxrc0916) |
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| 摘 要： | 目的:建立芫花药材的质量评价方法。方法:采用HPLC-DAD对21批芫花药材的指纹图谱进行比较研究,并用HPLC-ESI-MS技术对部分共有峰进行了初步归属。结果:建立了以16个共有峰为特征指纹信息的芫花药材的HPLC指纹图谱,并通过MS技术初步鉴定出其中10个共有峰所对应的可能化学成分,共有峰主要为黄酮苷及其苷元类成分。结论:该方法可为芫花药材指纹图谱和质量分析方法的建立提供参考。
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| 关 键 词： | 芫花 高效液相色谱 指纹图谱 ESI-MS分析 |
| 收稿时间： | 3/3/2011 12:00:00 AM |
HPLC Fingerprint of Flos Genkwa and Its ESI-MS Analysis |
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| DENG Shi-ren,XIA Lin-bo,DONG Qian,GUO Yan-hua and JIA Tian-zhu.HPLC Fingerprint of Flos Genkwa and Its ESI-MS Analysis[J].China Journal of Experimental Traditional Medical Formulae,2011,17(24):32-35. |
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| Authors: | DENG Shi-ren XIA Lin-bo DONG Qian GUO Yan-hua and JIA Tian-zhu |
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| Institution: | College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China;College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China;College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China;College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China;College of Pharmacy, Liaoning University of Traditional Chinese Medicine, Dalian 116600, China |
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| Abstract: | Objective : To establish a reliable and useful method for assessment of the quality of Flos Genkwa from different habitats. Method : Flos Genkwa from different habitats were analyzed by HPLC-DAD chromatographic fingerprint, some characteristic peaks were identified preliminarily based on the MS spectra and literature data. Results : Sixteen main characteristic peaks were selected from the fingerprint spectrum of 21 batches of samples, ten constituents of which were preliminarily identified as flavonoids and flavonoid glycosides. Conclusion : The method is valuable for quality control of Flos Genkwa. |
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| Keywords: | Flos Genkwa HPLC fingerprint ESI-MS analysis |
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