不透X线标志物检测胃排空对糖尿病胃轻瘫诊断试验的评价

目的评价不透X线标志物（ROMs）检测胃排空对糖尿病胃轻瘫的诊断效能及应用价值。方法对50例2型糖尿病患者采用ROMs法与核素显像法进行胃排空测定。分别记录6h胃排空率（GER）和胃半排空时间（GEt1/2），分析ROMs法诊断的敏感性与特异度。结果ROMs法6h胃排空率为100％时，敏感度、特异度分别为88．9％和81．3％；6h胃排空率为90％时，敏感度、特异度分别为72．2％和93．8％。受试者工作特性曲线下面积为0．884，Kappa值为0．67，糖尿病胃轻瘫发生率44％（22／50）。结论ROMs和核素显像检测胃排空具有良好的相关性，与金标准（核素显像）比较，ROMs法具有较高的特异度、准确度和Kappa值，一致性和信度好，且较简便，检测费用较低，适合糖尿病胃轻瘫的人群流行病学调查或社区发病学调查。

Radiopaque markers of gastric emptying for diagnosis of diabetic gastroparesis

Objective To evaluate Radiopaque markers of gastric emptying for diagnosis of diabetic gastro-paresis. Methods Fifty patients with type 2 diabetes mellitus were enrolled. The gastric empty were measured by radionuclide imaging ( RNI ), radiopaque markers ( ROMs), 6 hour gastric evacuation rate (GER) and Gel/2. Results The sensitivity and specificity were 88.9% and 81.3% respectively when 6 hour GER was 100%, and they were 72.2% and 93.8% respectively when 6 hour GER was 90%. The area under ROC curve and the Kappa value were 0. 884, 0.67, respectively. The prevalence of DGP was 44%. Conclusion There is close correlation between RNI and ROMs for measuring gastric emptying. ROMs is good for evaluating morbidity or epidemiology of DGP.