腹腔镜胆囊切除术后恶心呕吐相关因素的临床分析

目的探讨腹腔镜胆囊切除术后恶心呕吐（postoperative nausea and vomiting PONV）发生的相关临床因素。方法选取2003年3月至2007年10月行腹腔镜胆囊切除术患者160例，术前均无其他疾病和晕动病史，记录术后24h内患者恶心、呕吐情况，将其与年龄、性别、体重指数、麻醉时间、手术时间、气腹压力、手术后苏醒时间、芬太尼药量、术中胃肠胀气情况、术前使用镇痛药、术后使用镇痛药、术后24h平均血压等因素进行相关分析。结果PONV相关因素logistic回归分析发现与性别、体重指数、术前使用镇痛药、术后使用镇痛药、术后24h平均血压等预测变量有意义（P〈0．05）。结论性别、体重指数、术前使用镇痛药、术后使用镇痛药、术后24h平均血压影响PONV。

Factors related to nausea and vomiting after haparoscopic cholecystectomy

Objective To investigate correlation factors on postoperative nausea and vomiting after laparoscopic cholecystectomy.Methods One hundred and sixty case of laparoscopic cholecystectomy were chosen from our hospital without other disease preoperative.The incidence of nausea and vomiting in 24 hour after operation was observed, factors of age, gender, mean blood pressure of postoperative, baric index, pain-killer, dosage of fentanyl, stomach intestine tympanites interoperative, anaesthetic time, operative time...