儿童近视眼高阶像差与屈光度关系的分析

目的探讨睫状肌麻痹状态下儿童近视眼高阶像差与屈光度的关系。方法前瞻性系列研究。收集在我院就诊符合纳入标准的46例（83眼）近视眼和正视眼儿童，在睫状肌麻痹状态下应用iTrace视功能分析仪进行全眼波前像差的检测，提取瞳孔直径6mm时全眼的高阶RMS值（3-5阶）、3-5阶各项Zemike系数，比较不同屈光度分组之间全眼高阶像差RMS值（3-5阶）、3-5阶各项Zemike系数的差异及近视眼组高阶像差与屈光度的关系。结果低度近视组与正视眼组比较C40差异有统计学意义（P〈0．05）；不同屈光度分组问比较，4、5阶RMS值组间差异有统计学意义，其他3-5阶各项Zernike系数、总RMS值、3阶RMS值组间差异无统计学意义（P〉0．05）；近视眼组总高阶像差与等效球镜屈光度值无相关性。结论儿童近视眼高阶像差与近视屈光度无相关性。

Changes of higher-order wavefront aberrations as a function of the degree of myopia in children.

Objective To study the changes as a function of the degree of mypia in children after cycloplegia. Methods Prospective studies. Using the i-Trace visual function analyzer, root mean square （RMS） of total HOAs, 3rd-, 4th-, 5th- order aberrations were computed from the central 6.0mm zone of 83 eyes of 46 subjects RMS values （3rd-,4th- and 5th-order aberrations to total higher-order aberrations） of total HOAs and Zernike coefficients （3d-, 4th- and 5th-order aberrations ） were compared across the three refractive groups. Correlation analysis was performed to assess the association between HOAs and refractive power. Results Significant differences were found in C40 be- tween mild myopia and emmetropic. Significant differences were found in 4th-, 5th- order aberrations （P 〈 0.05） a- mong the different groups. No significant relationships were found between myopia and RMS of total HOAs. Conclu- sions No significant relationships were found between myopia and RMS of total HOAs.