| 5例宫颈微偏腺癌的临床分析 |
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| 引用本文： | 常洁,张莘,周晖,梁金晓,林仲秋.5例宫颈微偏腺癌的临床分析[J].癌症,2008,27(12):1310-1314. |
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| 作者姓名： | 常洁 张莘 周晖 梁金晓 林仲秋 |
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| 作者单位： | 中山大学附属第二医院妇瘤科,广东广州510120 |
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| 摘 要： | 背景与目的:宫颈微偏腺癌(minimal deviation adenocarcinoma of cervix, MDA)是一种罕见疾病,误诊率较高,尚无规范的治疗方法.本研究旨在分析总结MDA的临床病理特点,以提高对该病的认识.方法:回顾性分析中山大学附属第二医院1991年1月至2006年12月诊治的5例MDA患者的临床病理资料.结果:5例患者的中位年龄47岁(38～59岁).主要临床表现为大量稀薄粘液性白带、阴道不规则出血等.MDA在组织学上表现为腺体分化好,镜下难与宫颈内膜的正常腺体相区别,但浸润深度超过正常宫颈腺体的深度.免疫组化示2例患者癌胚抗原(CEA)和P53阳性.4例患者接受手术治疗,其中手术+放疗1例,手术+化疗+放疗3例;1例不能手术的患者接受了姑息性放疗.随访6～88个月,无失访病例,2例无瘤生存的患者中有1例无瘤生存时间超过5年,3例死于肿瘤复发转移.结论:MDA的诊断主要依靠临床表现和腺体浸润深度超过正常宫颈腺体深度的病理特点,以手术为主的综合治疗可能是治疗MDA的较好方法.
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| 关 键 词： | 宫颈肿瘤 微偏腺癌 诊断 治疗 预后 |
Clinical Analysis of Minimal Deviation Adenocarcinoma of the Cervix: A Report of Five Cases |
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| CHANG Jie,ZHANG Shen,ZHOU Hui,LIANG Jin-Xiao,LIN Zhong-Qiu.Clinical Analysis of Minimal Deviation Adenocarcinoma of the Cervix: A Report of Five Cases[J].Chinese Journal of Cancer,2008,27(12):1310-1314. |
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| Authors: | CHANG Jie ZHANG Shen ZHOU Hui LIANG Jin-Xiao LIN Zhong-Qiu |
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| Institution: | CHANG Jie,ZHANG Shen,ZHOU Hui,LIANG Jin-Xiao,LIN Zhong-QiuDepartment of Gynecological Oncology,The Second Affiliated Hospital,Sun Yat-sen University,Guangzhou,Guangdong,510120,P.R. China |
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| Abstract: | BACKGROUND & OBJECTIVE: The minimal deviation adeno- carcinoma (MDA) of the cervix is a rare disease. The misdiagnosis rate of this disease is relatively high and there is no standard treatment for it. This study was to evaluate clinicopathologic features, diagnosis, and treatment of MDA. METHODS: Records of five patients with MDA treated in the Second Affiliated Hospital of Sun Yet-sen University from Jan. 1991 to Dec. 2006 were retrospectively analyzed. RESULTS: The median age of the five patients was 47 ... |
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| Keywords: | Cervical neoplasms Minimal deviation adenocarcinoma Diagnosis Treatments Prognosis |
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