华法林预防冠脉支架术后78例血栓形成的疗效

目的: 观察华法林预防冠脉支架术后血栓形成的有效性和安全性。方法: 冠脉支架术后患者78例分为2组，金属裸支架组和药物涂层支架组。在常规治疗的基础上，调整华法林剂量，使INR值保持在2.0左右，观察早期和晚期支架术后患者心绞痛、心肌梗死等临床急性事件的发生及出血并发症。结果: 使用华法林后，两组早期未见临床急性事件出现，也未见出血并发症，晚期出现心绞痛两组分别为3例与1例，未发生心肌梗死事件和出血。对4例心绞痛患者再次行冠脉造影显示，置入支架处未见血栓及再狭窄，而是其他血管和血管段出现了冠脉狭窄。结论: 华法林可防止冠脉支架术后血管形成的急性事件，无论是金属裸支架或药物支架，只要剂量适当，这种作用是安全有效的。

Clinical effects of warfarin on prevention of stent thrombosis after percutaneous coronary intervention

AIM: To observe the clinical safety and effectiveness of warfarin on the prevention of stent thrombosis after percutaneous coronary intervention(PCI).METHODS: Of the 78 patients who were treated with stents,48 patients with bare-metal stents were enrolled in group A and 30 patients with drug-eluting stents in group B.The clinical manifestations of the two groups were similar.All patients received routine treatment and adjusted dose of warfarin(international normalized ratio 1.5-2.0).We observed and compared...