子痫前期产妇产后高血压的发病情况及其危险因素分析

目的 探讨子痫前期(PE)产妇产后高血压的发病情况及其危险因素。方法 从2012年1月-2016年12月在杭州市第一人民医院产科住院分娩的PE产妇中随机抽取860例作为研究对象,采用前瞻性研究的方法,收集其产前的一般情况资料、体格检查资料及实验室检查资料信息,并进行随访,评估其产后高血压发病情况,对PE产妇产后高血压发病危险因素进行单因素和多因素非条件logistic回归分析。结果 PE产妇产后高血压发病率为25.36%。单因素分析显示高血压家族史、产前收缩压高、产前舒张压高、产前FPG高、产前TG高、产前TC高均为PE产妇产后高血压发病的危险因素(P＜0.05),未发现年龄、吸烟史或被动吸烟史、饮酒史、口服短效避孕药史、孕前BMI、产前HDL-C、产前LDL-C为PE产妇产后高血压发病的危险因素(P＞0.05);多因素分析发现产前收缩压高(OR=3.827)、产前舒张压高(OR=3.353)、产前空腹血糖高(OR=3.136)、产前甘油三酯高(OR=2.809)均为PE产妇产后高血压发病的危险因素。结论 PE产妇产后高血压发病率比较高,达到25.36%,产前收缩压、舒张压、空腹血糖、甘油三酯高均为PE产妇产后高血压发病的危险因素。

Prevalence and risk factors of postpartum hypertension in women with a history of preeclampsia

Objective To investigate the prevalence of postpartum hypertension and its risk factors in women with a history of preeclampsia (PE). Methods A total of 860 PE women who delivered babies in Obstetrical Department of Hangzhou First People's Hospital from January 2012 to December 2016 were randomly selected as the research subjects. A prospective study was used to collect their prenatal general information, physical examination and laboratory detection data, and a follow-up was conducted to assess the prevalence of postpartum hypertension. Univariate and multivariate non-conditional logistic regression analyses were used to identify the risk factors of postpartum hypertension in the PE women. Results The prevalence rate of postpartum hypertension in the PE women was 25.36%. Single factor analysis showed that family history of hypertension, high systolic blood pressure, high diastolic blood pressure, high fasting plasma glucose (FPG), high triglyceride (TG) and high total cholesterol (TC) during the prenatal period were the risk factors of postpartum hypertension in the PE women (P<0.05). Age, history of smoking or passive smoking, drinking history, history of taking oral short-acting contraceptives, pre-pregnancy body mass index (BMI), prenatal high density lipoprotein cholesterol (HDL-C) and prenatal low density lipoprotein cholesterol (LDL-C) were not the risk factors of postpartum hypertension in the PE women (P>0.05). Multivariate analysis showed that high systolic blood pressure (OR=3.827), high diastolic blood pressure (OR=3.353), high FPG (OR=3.136) and high TG (OR=2.809) during the prenatal period were the risk factors for postpartum hypertension in the PE women. Conclusions The prevalence rate of postpartum hypertension in the PE women is relatively high, reaching 25.36%. Elevated systolicand diastolic blood pressure, high FPG and high TG during the prenatal period are all the risk factors for postpartum hypertension in the PE women.