| 结核分枝杆菌L型特征及临床意义研究进展 |
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| 引用本文： | 刘栋宾,向延根,马小华,石国民,陈拥军,彭雪峰. 结核分枝杆菌L型特征及临床意义研究进展[J]. 实用预防医学, 2018, 25(9): 1150-1153. DOI: 10.3969/j.issn.1006-3110.2018.09.037 |
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| 作者姓名： | 刘栋宾 向延根 马小华 石国民 陈拥军 彭雪峰 |
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| 作者单位： | 1.南华大学,湖南衡阳421001;2.长沙市中心医院 |
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| 基金项目： | 湖南省卫生和计生委员会科研课题(B2016156);院内科研立项课题(YNKY201811) |
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| 摘 要： | 结核病是影响公共卫生健康安全的一种慢性传染性疾病。其病原菌是结核分枝杆菌(Mycobacterium tuberculosis,MTB),而结核分枝杆菌L型(Mycobacterium tuberculosis L-forms,MTB-L)是MTB细胞壁缺失的一种特殊形态,在显微镜下呈现抗酸染色阴性、形态多样的特点,且目前临床实验室检测率低,较难发现。近年来MTB-L型在临床中的报道越来越多,本文通过对MTB-L的生物学特征、耐药性和临床致病力等方面进行综述。
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| 关 键 词： | 结核分枝杆菌 L型 研究进展 |
| 收稿时间： | 2018-03-01 |
Research progress on characteristics and clinical significanceof Mycobacterium tuberculosis L-form |
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| LIU Dong-bin,XIANG Yan-gen,MA Xiao-hua,SHI Guo-min,CHEN Yong-jun,PENG Xue-feng. Research progress on characteristics and clinical significanceof Mycobacterium tuberculosis L-form[J]. Practical Preventive Medicine, 2018, 25(9): 1150-1153. DOI: 10.3969/j.issn.1006-3110.2018.09.037 |
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| Authors: | LIU Dong-bin XIANG Yan-gen MA Xiao-hua SHI Guo-min CHEN Yong-jun PENG Xue-feng |
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| Affiliation: | University of South China, Hengyang, Hunan 421001, China |
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| Abstract: | Tuberculosis is a chronic infectious disease affecting public health and safety, and its pathogen is Mycobacterium tuberculosis (MTB). Mycobacterium tuberculosis L-form (MTB-L) is a cell wall deficient form of Mycobacterium tuberculosis, its characteristics under microscope present negative acid-fast stain and various shapes; moreover, the current clinical laboratory detection rate is low. There are more and more clinical reports of MTB-L in recent years, and this article summarizes the biological characteristics, drug resistance and clinical pathogenicity of MTB-L.
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| Keywords: | Mycobacterium tuberculosis L-form research progress |
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