早产儿宫外生长迟缓发生情况及相关危险因素研究

目的对早产儿宫外生长发育迟缓(EUGR)的发生情况及相关危险因素进行了临床研究,为临床中减少早产儿EUGR提供理论指导。方法对南山医院2009年1月-2011年12月新生儿科住院的早产儿,共357例,对发生EUGR的危险因素进行分析。结果 <32周组、32～35周组和>35周组按照出生体重和出生头围评价,差异无统计学意义(P>0.05);<1500 g组、1500 g～组和≥2500 g组按照出生体重和出生头围评价,差异均有统计学意义(P<0.05)。危险因素纳入多因素Logistic回归分析,得出体重EUGR的危险因素:出生胎龄、出生体重。头围EUGR的危险因素:出生头围、是否头围IUGR和静脉氨基酸最大量。结论指导孕妇加强营养支持,避免影响早产的各种因素,同时,早期给予出生后早产儿充足的能量及各种营养素,均有利于患儿未来的体格及智力发育。

Prevalence and Risk Factors for Extrauterine Growth Retardation of Premature Infants

Objective To study the prevalence and risk factors for the extrauterine growth retardation(EUGR) and provide a theoretical guidance for clinic.Methods The data of 357 cases of premature infants in our department from January 2009 to December 2011 were summarized to analyze the risk factors for EUGR.Results According to birth weight and birth head circumference evaluation,there was not statistically significant about <32 weeks group,32 to 35 weeks and >35 weeks groups(P>0.05);There were statistically significant about <1500 g group,1500 g group and the 2500g groups(P<0.05).The multi-factor logistic regression analysis revealed that the risk factors about weight EUGR:gestational age,birth weight.Risk factors about head circumference EUGR: birth head circumference,head circumference in IUGR and the maximum amount of intravenous amino acids.Conclusion Pregnant women should give the nutritional support and guidance to avoid a variety of factors that affect preterm.