不典型鳞状上皮细胞筛查的临床价值

目的探讨不典型鳞状上皮细胞(ASC)在宫颈病变中的临床意义及阴道镜对ASC再分类的临床价值。方法对2009年5月-2011年10月医院95例细胞学检查结果为ASC的患者,行阴道镜检查及定位活检,与临床病理资料对比分析。结果 ASCUS组患者诊断为CINⅠ、CINⅡ、CINⅢ共36例,占40.5%,ASC-H组患者诊断为CINⅠ、CINⅡ、CINⅢ共5例,占83.3%,两组比较差异具有统计学意义(P<0.05)。阴道镜诊断的敏感性为87.8%,特异性为85.2%,阳性预测值为81.8%,阴性预测值为90.2%,与病理学结果具有较高的一致性。结论 ASC患者中潜存着高级别宫颈病变,阴道镜检查预测性高,有助于ASC的分层管理,提高宫颈病变检出率。

The Clinical Significance of Atypical Squamous Cell and the Value of Colposcopic Diagnosis in Redassincation of ASC

Objective To explore the clinical significance of atypical squamous cell(ASC) and evaluate the clinical value of colposcopic diagnosis in redassincation of ASC.Methods 95 cases of ASC from May 2009 to Oct.2011 were detected by biopsy under the colposcopy,and they were compared with final pathological diagnosis.Results 36 cases(40.5%) in ASCUS group were CIN Ⅰ,CIN Ⅱ,CIN Ⅲ,and 5 cases(83.3%) in ASC-H group.There was statistical difference between them(P<0.05).The sensitivity,specificity,positive prevalue,negative prevalue of colposcopic diagnosis were 87.8%,85.2%,81.8%,and 90.2%,respectively,which was high consistency with pathological diagnosis.Conclusion There was latent high grade cervical lesion.Colposcopic diagnosis had high forecasting value,which was favorable for shunting management in ASC and increasing the diagnosis of cervical lesion.