| 环氧合酶-2在成年雄性大鼠睾丸和附睾中的表达 |
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| 引用本文： | 侯晓妮,章汉旺,李豫峰. 环氧合酶-2在成年雄性大鼠睾丸和附睾中的表达[J]. 中华男科学杂志, 2005, 11(2): 104-105,111 |
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| 作者姓名： | 侯晓妮 章汉旺 李豫峰 |
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| 作者单位： | 华中科技大学同济医学院附属同济医院生殖医学中心,湖北,武汉,430030 |
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| 摘 要： | 目的:探讨环氧合酶 2在雄性大鼠睾丸和附睾组织中的表达及其意义。 方法:应用免疫组化SP法检测 40只雄性SD大鼠睾丸和附睾组织中环氧合酶 2的表达及其定位情况。 结果:环氧合酶 2在雄性大鼠的睾丸和 附睾组织中有较强的表达。在附睾头部主要表达于腔上皮细胞的细胞核内,部分细胞质内也可见表达,睾丸精原 细胞胞质和细胞核内均可见棕黄色颗粒。 结论:免疫组化法可较为敏感地检测环氧合酶 2在雄性大鼠睾丸和 附睾组织的表达。
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| 关 键 词： | 环氧合酶-2 睾丸 附睾 大鼠 |
| 文章编号： | 1009-3591(2005)02-0104-03 |
Expression of Cyclooxygenase-2 in the Testes and Epididymides of Adult Male Rats |
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| HOU Xiao-ni,ZHANG Han-wang,LI Yu-fengCenter of Reproductive Medicine,Tongji Hospital of Tongji Medical College,Huazhong University of Science and Technology,Wuhan,Hubei ,China. Expression of Cyclooxygenase-2 in the Testes and Epididymides of Adult Male Rats[J]. National journal of andrology, 2005, 11(2): 104-105,111 |
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| Authors: | HOU Xiao-ni ZHANG Han-wang LI Yu-fengCenter of Reproductive Medicine Tongji Hospital of Tongji Medical College Huazhong University of Science Technology Wuhan Hubei China |
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| Affiliation: | Center of Reproductive Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China. |
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| Abstract: | Objective: To investigate the expression of cyclooxygenase-2 (cox-2) in the testes and epididymides of adult male rats and its significance. Methods: Immunohistochemical staining was used to detect the expression and localization of cox-2 in the testicle and epididymal tissues of 40 adult male SD rats. Results: Strong cox-2 immunoreactivity was detected in the epididymides and testes of the rats. In the caput epididymides, cox-2 expressed mainly in the epithelial nuclei and partly in the cytoplasm. Cox-2 was also found positive in the testis nuclei and cytoplasm. Conclusion: Immunohistochemical staining is a fairly sensitive method for detecting cox-2 expression in the testes and epididymides of adult male rats. |
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| Keywords: | cyclooxygenase-2 testis epididymis rat |
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