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Clinical pathological analysis and immunohistochemical study of ten solitary fibrous tumors
Authors:Wang Huiping  Zhang Wei  Yan Liping  Yao Hongtian  Ding Wei  Yu Xinru
Institution:Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China
Abstract:Objective To study the clinical and pathological characteristics of solitary fibrous tumor (SFT) Methods Clinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT.Results The SFTs located variously and showed different histological features. All cases showed positive staining for CD(34), VM (vimentin) and Bcl-2, but negative staining for Desmin, S-100, CK (cytokeratin) and EMA (epithelial membrane antigen). Conclusions SFT is described as a 'patternless' growth pattern. According to clinical pathological features and immunohistochemistry, it is different from other soft tissue tumors. Long-term clinical follow-up is necessary for this kind of tumor
Keywords:solitary fibrous tumor  immunohistochemistry  pathology
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