Clinical pathological analysis and immunohistochemical study of ten solitary fibrous tumors |
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Authors: | Wang Huiping Zhang Wei Yan Liping Yao Hongtian Ding Wei Yu Xinru |
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Institution: | Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China;Department of Pathology, First Affiliated Hospital of Zhejiang University, Hangzhou 310003, China |
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Abstract: | Objective To study the clinical and pathological characteristics of solitary fibrous tumor (SFT) Methods Clinical pathological analysis and immunohistochemical studies were performed on ten patients with SFT.Results The SFTs located variously and showed different histological features. All cases showed positive staining for CD(34), VM (vimentin) and Bcl-2, but negative staining for Desmin, S-100, CK (cytokeratin) and EMA (epithelial membrane antigen). Conclusions SFT is described as a 'patternless' growth pattern. According to clinical pathological features and immunohistochemistry, it is different from other soft tissue tumors. Long-term clinical follow-up is necessary for this kind of tumor |
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Keywords: | solitary fibrous tumor immunohistochemistry pathology |
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