原发性巨块型肝细胞癌肿瘤血管形态分析及其生物学特性探讨

目的探讨原发性巨块型肝细胞癌多层螺旋CT动脉期的肿瘤血管及其生物学特性.方法回顾分析67例原发性巨块型肝细胞癌患者的多层螺旋CT增强扫描资料.结果原发性巨块型肝细胞癌多层螺旋CT动脉期肿瘤血管形态分6种类型:(1)车轮型16例(23.9%);(2)条状不规则型21例(31.3%);(3)放射型13例(19.4%);(4)稀细型7例(10.4%);(5)结节型6例(9%);(6)线球型4例(6%).第1型易中心坏死,形态较规则,边界较清.第5型边界不清,易侵犯门静脉.第6型边界清,血供最丰富.结论多层螺旋CT动脉期可显示原发性巨块型肝细胞癌的肿瘤血管形态及可反映肿瘤生物学特性,对指导临床选择治疗方案有重要的价值.

A study of the vessel morphous and biological character of primary hepatic cellular carcinoma (giant mass type) with multiple slices spinal CT

Objective To investigate the vessel morphous and biological character of primary hepatic cellular carcinoma (giant mass type) in arterial period of liver scanning with multiple slices spinal CT. Methods The appearances of focus in arterial period of liver scanning with multiple slices spinal CT were analyzed retrospectively in 67 cases with primary hepatic cellular carcinoma (giant mass type). Results The vessel morphous of focus in arterial period of liver scanning with multiple slices spinal CT was divided into six types- cartwheel pattern in 16 of 67 cases(23.9%)- irregular strip pattern in 21 of 67 cases(31.3%)- radial pattern in 13 of 67 cases(19.4%)- fine pattern in 7 of 67 cases (10.4%)- nodular pattern in 6 of 67 cases (9%)- spireme pattern in 4 of 67 cases (6%). The appearance of CT scanning in type I was necrosis in centre of focus with distinct boundary. The appearance of CT scanning in type V was obscure boundary of focus that was intended to invade portal vein. The appearance of CT scanning in type VI was distinct boundary of the focus with rich blood supply. Conclusions The arterial period of liver scanning with multiple slices spinal CT can reflexes the vessel morphous and biological character of primary hepatic cellular carcinoma (giant mass type) and is helpful choosing the therapeutic regimen.