高龄人群大肠肿瘤连续普查随防的意义

目的 了解高龄人群大肠癌普查的意义。方法 被查对象在不限制饮食的条件下留取晨起粪便20g,以序贯法进行隐血(SOB)检查。1994年以后加做粪免疫白蛋白(MA)试验,筛检阳性者均进行全结肠镜检查,发现大肠癌的均行手术切除,大肠腺瘤均在肠镜下行电切并每年内镜随访。结果 SOB阳性232人,其中大肠癌3例,临床分期为DUKES'B期2例,DUKES'A期1例。大肠腺瘤130例,有9例间期癌,临床分期以C、D期为多。MA阳性者137例,合并隐血阳性的大肠癌2例,均为间期癌。结论 每年高龄人群SOB、MA普查有一定意义,及时对大肠腺瘤行干涉治疗对高龄人群大肠癌的预防有重要意义。

Periodical Mass Screening of Colorectal Neoplasms in Senior Population for 11 years

Objective To evaluate the effect of mass screening for colorectal Neoplasma in senior population. Methods 20g of stool was collected without diet control and fecal occult blood (OB) was tested by means of sequencial OB(SOB). Fecal tracing alumin(TA) test had been added since 1994. Either or TA was positive, colonoscopy was checked. Cases with colorectal cancer were operated on and those with polyps of adenomas were removed and followed up yearly with endoscope. Results Of the 232 cases with positive SOB,3 were found to have carcinoma staging Duke's A. 130 were of adenoma 9 cases of cancer had been clinically diagnosed during periodical screening, and most of the tumours staged Duke's C, D. 137 subjects were TA positive , and 2 cases of cancer clinically diganosed were noticed to be both OB & TA positive. Conclution Periodical mass screening of colorectal neoplasm by means of OB & TA in senior population is necessary, and the removal of adenoma is helpful in prevention of senior population from carciongeneses.