针灸治疗非酒精性脂肪性肝炎的临床观察

观察针灸疗法治疗非酒精性脂肪性肝炎的临床疗效。【方法】采用随机数字表法将108例患者随机分为两组。电针组(60例)取丰隆穴电针治疗,留针10 min,每天治疗1次,连续治疗6 d后休息1 d,共治疗8周。西药组(48例) 每天给予西药阿托伐他汀片10 mg,1次／d,口服;肝泰乐片0．2 g,3次／d,口服,连续治疗8周。观察两组临床疗效,检测两组治疗前后肝功能指标及血脂水平、肝纤维化指标,同时观察患者的不良反应。【结果】电针组总有效率为91．70％, 西药组为83．30％,电针组疗效优于西药组(P<0．01)。治疗后两组的肝功能指标、血脂水平及肝纤维化指标均有改善 (与治疗前比较,P<0．05或P<0．01),且电针组的改善作用均较西药组好(P<0．05或P<0.01)。西药组部分患者出现恶心、消化不良症状,电针组未发现任何不良反应。【结论】电针丰隆穴能改善非酒精性脂肪性肝炎患者的临床症状,改善肝功能,降低血脂水平和抗肝纤维化作用,对非酒精性脂肪性肝炎有较好的治疗作用。

Clinical Observation on Electroacupuncture for Nonalcoholic Steatohepatitis

Objective] To observe the therapeutic effect of electroacupuncture (EA) for nonalcoholic steatohepatitis (NASH). Methods] One hundred and eight cases were randomized into two groups. Sixty NASH patients in EA group (group A) were treated by EA on Fenglong point with needie retaining for 10 min, once per day, breaking for one day after a 6-day treatment and repeating the treatment in the following weeks. Forty-eight in positive control group (group B) were given glucrolactone 0.2 g, tid and atorvastatin Tablets 10 mg, qd for 8 weeks. The therapeutic effect in the two groups was evaluated after treatment and the parameters of hepatic function, blood lipid and hepatic fibrosis, as well as the adverse reaction were observed before and after treatment. Results] The total effective rate was 91.70% in EA group and 83.30% in the positive control group, the difference being significant (P<0.01). After treatment, parameters of hepatic function, blood lipid and hepatic fibrosis were improved in EA group (P<0.05 or P<0.01 as compared with those before treatment) , the improvement being obvious compared with the positive control group (P< 0.05 or P<0.01). Adverse reactions such as nausea and dyspepsia were found in some patients of the positive control group but not found in EA group. Conclusion] EA on Fenglong point is effective for the treatment of NASH in relieving symptoms, improving hepatic function, decreasing blood lipid and counteracting hepatic fibrosis.