| 国产替考拉宁对耐甲氧西林表皮葡萄球菌的体外抗菌活性观察 |
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| 引用本文： | 李仲兴,张立志,王秀华,张明明,时东彦. 国产替考拉宁对耐甲氧西林表皮葡萄球菌的体外抗菌活性观察[J]. 中国抗生素杂志, 2002, 27(8): 490-492,503 |
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| 作者姓名： | 李仲兴 张立志 王秀华 张明明 时东彦 |
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| 作者单位： | 1. 河北医科大学第二医院,石家庄,050000
2. 河北省人民医院,石家庄,050071 |
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| 摘 要： | 评价国产替考拉宁对耐甲氧西林表皮葡萄球菌（MRSE）和甲氧西林敏感表皮葡萄球菌（MSSE）的体外抗菌活性，用琼脂二倍稀释法测定了84株MRSE和28株MSSE临床菌株的最低抑菌浓度，并与万古霉素进行了比较，结果表明国产替考拉宁对48株MRSE和28株MSSE抑菌效果较好，其敏感率分别为97．62％和100％。
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| 关 键 词： | 替考拉宁 耐甲氧西林表皮葡萄球菌 体外抗菌活性 万古霉素 甲氧西林敏感表皮葡萄球菌 糖肽类抗生素 琼脂二倍稀释法 |
| 文章编号： | 1001-8689(2002)08-0490-03 |
Observation of in vitro antibacterial activity of domestic teicoplanin against methicillin-resistent Staphylococcus epidermidis |
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| Li Zhong xing ,Zhang Li zhi ,Wang Xiu hua ,Zhang Ming ming and Shi Dong yan. Observation of in vitro antibacterial activity of domestic teicoplanin against methicillin-resistent Staphylococcus epidermidis[J]. Chinese Journal of Antibiotics, 2002, 27(8): 490-492,503 |
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| Authors: | Li Zhong xing Zhang Li zhi Wang Xiu hua Zhang Ming ming Shi Dong yan |
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| Affiliation: | Li Zhong xing 1,Zhang Li zhi 2,Wang Xiu hua 1,Zhang Ming ming and Shi Dong yan 1 |
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| Abstract: | To evaluate the antibacterial activity of domestic teicoplanin against methicillin resistent Staphylococcus epidermidis (MRSE) and methicillin sensitive Staphylococcus epidermidis (MSSE). Determination of antibacterial activity of domestic teicoplanin against MRSE (84 strains) and MSSE (28 strains) was performed by using agar dilution method. The in vitro antibacterial activity of teicoplanin was compared with that of vancomycin. Results showed that the antibacterial efficacy of domestic teicoplanin against MRSE (84 strains) and MSSE (28 strains) was good . The sensitivity rate of teicoplanin against MRSE and MSSE 97.62% and 100% respectively. |
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| Keywords: | Teicoplanin Vancomycin Methicillin resistent Staphylococcus epidermidis (MRSE) Methicillin sensitive Staphylococcus epidermidis (MSSE) In vitro antibacterial activity |
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