| 缺血后处理对肾脏缺血再灌注大鼠氧化亚氮系统的影响 |
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| 引用本文： | 鸦杏鹏,周留正,孙浩.缺血后处理对肾脏缺血再灌注大鼠氧化亚氮系统的影响[J].江苏大学学报(医学版),2011,21(5):378-381. |
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| 作者姓名： | 鸦杏鹏 周留正 孙浩 |
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| 作者单位： | 1. 句容市人民医院泌尿外科,江苏,句容,212400
2. 江苏大学附属医院泌尿外科,江苏,镇江,212001 |
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| 摘 要： | 目的:观察大鼠肾脏缺血后处理对氧化亚氮合酶的影响,探讨缺血后处理对肾缺血再灌注损伤的影响机制.方法:SD大鼠30只,分为假手术组、缺血再灌注组、缺血后处理组.缺血45 min再灌注24 h后取肾组织检测氧化亚氮(NO)含量、氧化亚氮合酶(NOS)活性、超氧化物歧化酶(SOD)活性、丙二醛(MDA)含量,HE染色进行中性...
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| 关 键 词： | 缺血后处理 肾缺血再灌注损伤 氧化亚氮 氧化亚氮合酶 |
Effect of ischemic post-conditioning on NO expression during renal ischemic reperfusion injury in rat |
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| YA Xin-pen,ZHOU Liu-zheng,SUN Hao.Effect of ischemic post-conditioning on NO expression during renal ischemic reperfusion injury in rat[J].Journal of Jiangsu University Medicine Edition,2011,21(5):378-381. |
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| Authors: | YA Xin-pen ZHOU Liu-zheng SUN Hao |
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| Institution: | YA Xin-pen1,ZHOU Liu-zheng2,SUN Hao2(1.Department of Urology,the People's Hospital of Jurong,Jurong Jiangsu 212400,2.Department of Urology,the Affiliated Hospital of Jiangsu University,Zhenjiang Jiangsu 212001,China) |
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| Abstract: | Objective: To observe the change of NO,NOS expression during renal ischemic reperfusion injury in rat after ischemic post-conditioning and to investigate the effect of ischemic post-conditioning on ischemic/reperfusion induced renal injury.Methods: Thirty SD rats were randomly divided into three groups: sham-operated group,ischemic-reperfusion group,ischemic post-conditioning group.The renal underwent 45-minute ischemic and 24-hour reperfusion.The level of Superoxide Dismutase(SOD),Malondialdehyde(MDA),NO,N... |
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| Keywords: | ischemic post-conditioning kidney ischemic reperfusion injury NO NOS |
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