Diagnostic challenges in thyroid cytopathology |
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Affiliation: | 1. Department of Pathology, Charles University, Medical Faculty and Charles University Hospital Plzen, Czech Republic;2. Department of Pathology, University of British Columbia, Royal Columbian Hospital, Vancouver, Canada;3. Department of Urology, Charles University, Medical Faculty and Charles University Hospital Plzen, Czech Republic;4. Department of Pathology, Instituto Nacional de Cancerologia, Mexico City, Mexico;5. Department of Pathology, University Clinical Center, Sarajevo, Bosnia and Herzegovina;6. “Ljudevit Jurak” Pathology Department, Clinical Hospital Center “Sestre milosrdnice,“, Zagreb, Croatia;7. Biopticka Laborator, Plzen, Czech Republic;8. Department of Radiodiology, Charles University, Medical Faculty and Charles University Hospital Plzen, Czech Republic;9. Department of Pathology, The University of Kansas School of Medicine, Kansas City, KS |
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Abstract: | Fine needle aspiration (FNA) is a long-standing modality used to obtain diagnostic material from patients with thyroid nodules. However, some common and uncommon situations exist in which diagnostic categorization of an FNA specimen is not straightforward. Diagnostically challenging thyroid lesions are typically either benign entities with cytomorphology that mimics malignancy, or malignant entities with unusual cytomorphology that causes difficulty in classification. Awareness of such diagnostic challenges can help broaden one's differential diagnosis when encountering such lesions on FNA. However, in many instances a definitive diagnosis may not be possible and providing an indeterminate diagnosis is most appropriate. |
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Keywords: | fine needle aspiration papillary thyroid carcinoma the Bethesda System for Reporting Thyroid Cytopathology thyroid |
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