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Innovative approach in the development of computer assisted algorithm for spine pedicle screw placement
Institution:1. Houston Methodist Hospital, Houston, Texas, U.S.A.;2. Institute of Orthopedic Research & Education, Houston, Texas, U.S.A.;1. Laboratory of Cancer Prevention, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA;2. Science Applications International Corporation-Frederick, National Cancer Institute, Frederick, MD, USA;3. Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA;1. Hospital Prof Doutor Fernando Fonseca, Amadora, Portugal;2. Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade de Lisboa, 1649-028 Lisbon, Portugal;3. Parkinson''s Disease and Movement Disorders Center, Division of Neurology, Department of Medicine, The Ottawa Hospital Research Institute, University of Ottawa Brain and Mind Institute, Ottawa, ON, Canada;4. Clinical Pharmacology Lab, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal;5. Institute of Physiology, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal;6. Department of Neurosciences and Mental Health, Neurology, Hospital de Santa Maria, Lisbon, Portugal;7. Campus Neurológico Sénior, Torres Vedras, Portugal;1. Associate Professor, Dept of Orthopaedics, Armed Forces Medical College, Pune 411040, India;2. Professor and Head, Dept of Orthopaedics, Armed Forces Medical College, Pune 411040, India;3. Resident, Dept of Orthopaedics, Armed Forces Medical College, Pune 411040, India
Abstract:Pedicle screws are typically used for fusion, percutaneous fixation, and means of gripping a spinal segment. The screws act as a rigid and stable anchor points to bridge and connect with a rod as part of a construct. The foundation of the fusion is directly related to the placement of these screws. Malposition of pedicle screws causes intraoperative complications such as pedicle fractures and dural lesions and is a contributing factor to fusion failure. Computer assisted spine surgery (CASS) and patient-specific drill templates were developed to reduce this failure rate, but the trajectory of the screws remains a decision driven by anatomical landmarks often not easily defined. Current data shows the need of a robust and reliable technique that prevents screw misplacement. Furthermore, there is a need to enhance screw insertion guides to overcome the distortion of anatomical landmarks, which is viewed as a limiting factor by current techniques. The objective of this study is to develop a method and mathematical lemmas that are fundamental to the development of computer algorithms for pedicle screw placement. Using the proposed methodology, we show how we can generate automated optimal safe screw insertion trajectories based on the identification of a set of intrinsic parameters. The results, obtained from the validation of the proposed method on two full thoracic segments, are similar to previous morphological studies. The simplicity of the method, being pedicle arch based, is applicable to vertebrae where landmarks are either not well defined, altered or distorted.
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