The eye and inflammatory rheumatic diseases: The eye and rheumatoid arthritis,ankylosing spondylitis,psoriatic arthritis |
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| Institution: | 1. St. Luke''s Cataract and Laser Institute, Tarpon Springs, Florida;2. Departments of Ophthalmology and Medicine, the Mount Sinai Medical School, New York, New York; Department of Epidemiology, the Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland;3. Department of Ophthalmology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama;4. Departments of Ophthalmology and Medicine, Division of Rheumatology, Oregon Health & Science University, Portland, Oregon;5. Department of Ophthalmology, Legacy Devers Eye Institute, Portland, Oregon;6. Department of Ophthalmology, Moran Eye Institute, University of Utah School of Medicine, Salt Lake City, Utah;7. Departments of Ophthalmology, Pathology, and Biological Structure, University of Washington School of Medicine, Seattle, Washington;1. Rheumatology Division, Hospital de La Princesa, IIS-IP, Universidad Autónoma de Madrid (UAM), c/ Diego de León 62, 28006 Madrid, Spain;2. Amsterdam Rheumatology and Immunology Center, VU University Medical Center, Reade P.O. Box 7057, 1007 MB Amsterdam, The Netherlands;3. University of Cantabria, Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Rheumatology Division, Hospital Universitario Marqués de Valdecilla, Avda. de Valdecilla, s/n, 39008 Santander, Spain;1. Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts;2. Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts;3. Department of Ophthalmology, The Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pennsylvania;4. Department of Population, Family, and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD;5. Department of Ophthalmology, The Johns Hopkins School of Medicine, Baltimore, Maryland;6. Department of Ophthalmology, Boston Children’s Hospital, Boston, Massachusetts;7. Massachusetts Eye Research and Surgery Institution, Waltham, Massachusetts;8. Department of Ophthalmology, Somdech Phra Pinkloa Hospital, Royal Thai Navy, Bangkok, Thailand;9. Department of Ophthalmology, Chulalongkorn University, Bangkok, Thailand;10. Siddharth Netralaya, Belgaum, Karnataka, India;11. Departments of Ophthalmology and Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York;12. Department of Epidemiology, The Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland;13. Laboratory of Immunology, National Eye Institute, National Institutes of Health, Bethesda, Maryland;14. Department of Ophthalmology, Oregon Health and Science University, Portland, Oregon;15. Department of Medicine, Oregon Health and Science University, Portland, Oregon;16. Legacy Devers Eye Institute, Portland, Oregon;17. The Tampa Bay Uveitis Center, St. Petersburg, Florida;18. Department of Ophthalmology, Portland Veteran’s Affairs Medical Center, Portland, Oregon;19. MCM Eye Unit, MyungSung Christian Medical Center and MyungSung Medical School, Addis Ababa, Ethiopia |
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| Abstract: | Rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis are associated with potentially sight-threatening inflammatory eye disease. Although the ocular manifestations associated with ankylosing spondylitis and psoriatic arthritis are similar, such as anterior uveitis, this differs from rheumatoid arthritis where dry eye, peripheral ulcerative keratitis and scleritis are the major ocular complications. Apart from causing sight loss, these conditions are painful, debilitating, often recurrent or chronic and may require long-term therapy. Treatments such as ocular lubricant, topical corticosteroid, systemic corticosteroid and systemic immunosuppression are often similar for the underlying systemic disease. Yet for the treatment of the ocular complications, the evidence base is weak. Close collaboration with a rheumatologist is often essential, particularly in the management of these patients. |
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| Keywords: | Dry eye Peripheral ulcerative keratitis Scleritis Anterior uveitis |
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