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Curtailed T‐cell activation curbs effector differentiation and generates CD8+ T cells with a naturally‐occurring memory stem cell phenotype
Authors:Veronica Zanon  Karolina Pilipow  Eloise Scamardella  Federica De Paoli  Gabriele De Simone  David A Price  Amaia Martinez Usatorre  Pedro Romero  Domenico Mavilio  Alessandra Roberto  Enrico Lugli
Institution:1. Laboratory of Translational Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy;2. Institution of Infection and Immunity, Cardiff University School of Medicine, Cardiff, Wales, UK;3. Translational Tumor Immunology Group, Ludwig Center for Cancer Research, Epalinges, Switzerland;4. Unit of Clinical and Experimental Immunology, Humanitas Clinical and Research Center, Rozzano, Milan, Italy;5. Department of Medical Biotechnologies and Translational Medicine (BioMeTra), University of Milan, Italy, Milan;6. Humanitas Flow Cytometry Core, Humanitas Clinical and Research Center, Rozzano, Milan, Italy
Abstract:
Keywords:Adoptive cell transfer  CD8+  Effector T cells  T‐cell activation  T memory stem cells
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