| 高精度散射光度滴定法在苯妥英钠含量测定中的应用 |
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| 引用本文： | 易涛,詹先成,李成容,何宁.高精度散射光度滴定法在苯妥英钠含量测定中的应用[J].药学学报,2006,41(4):370-375. |
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| 作者姓名： | 易涛 詹先成 李成容 何宁 |
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| 作者单位： | 四川大学,华西药学院,四川,成都,610041 |
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| 摘 要： | 目的用高精度散射光度滴定法测定苯妥英钠。方法测定了苯妥英银凝胶的溶度积常数，研究了滴定的最优条件。结果滴定结果与对照试验测定结果无显著差异。结论用高精度散射光度滴定法测定苯妥英钠结果准确、重复性好、专属性强、线性范围宽。
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| 关 键 词： | 高精度散射光度滴定法 苯妥英钠 溶度积常数 凝胶 |
| 文章编号： | 0513-4870（2006）04-0370-06 |
| 收稿时间： | 2005-06-24 |
| 修稿时间： | 2005-06-24 |
Application of highly accurate nephelometric titration in the assaying of phenytoin sodium |
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| YI Tao,ZHAN Xian-cheng,LI Cheng-rong,HE Ning.Application of highly accurate nephelometric titration in the assaying of phenytoin sodium[J].Acta Pharmaceutica Sinica,2006,41(4):370-375. |
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| Authors: | YI Tao ZHAN Xian-cheng LI Cheng-rong HE Ning |
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| Institution: | West China School of Pharmacy, Sichuan University, Chengdu 610041, China |
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| Abstract: | Aim To determine phenytoin sodium by a highly accurate nephelometric titration. Methods The titration operating conditions were optimized and the solubility product constant of phenytoin silver precipitation was determined. Results The result of the titration is comparable to those of control experiments. Conclusion The proposed method has been found to be accurate, precise, specific, reproducible, and linear. |
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| Keywords: | highly accurate nephelometric titration phenytoin sodium solubility product constant colloid |
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