老年脑梗死与颈动脉粥样硬化关系的临床研究

目的　探讨老年脑梗死与颈动脉粥样硬化的关系。方法　应用彩色多普勒超声对 1 0 8例老年脑梗死患者及 86例同龄无明显心脑血管病患者进行对照研究 ,观察其颈动脉内膜 -中膜厚度 (IMT)、斑块结构及管腔狭窄情况。结果　脑梗死组颈动脉斑块发生率为 82 .41 % ,显著高于对照组 (48.84% ) (P<0 .0 0 0 1 )。斑块类型中软斑块及溃疡斑所占的比率、颈总动脉 IMT增厚和颈动脉中度 (50 %～ 70 % )及重度 (>70 % )狭窄的发生率脑梗死组高于对照组 ,差异均有显著性意义。结论　老年人颈动脉粥样硬化斑块类型 ,IMT增厚及管腔狭窄程度与脑梗死密切相关。

Clinical study on relationship between carotid atherosclerosis and cerebral infarction in the elderly

Objective To explore the relationship between carotid atherosclerosis and cerebral infarction in the elderly Methods With color Doppler ultrasonography, the comparative study in 108 elder cerebral infarction patients and 86 controls age matched and free of stroke and heart diseases was applied to examine the carotid intima media thickness (IMT), plaque structure and the degree of artery stenosis Results The prevalence of carotid plaque in the patients was significantly higher than that in controls (82 41% vs 48 84%, P < 0 0001) The rates of soft and ulcerated carotid plaque, the incidence of intima media thickening in common carotid and the incidence of moderate (50%~70%) and severe (>70%) stenosis in carotid were significantly higher in patients compared with controls Conclusions The carotid plaque type, IMT and the degree of stenosis were positively related to cerebral infarction in the elderly