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Comparison of MGIT and Myco/F Lytic Liquid-Based Blood Culture Systems for Recovery of Mycobacterium tuberculosis from Pleural Fluid
Authors:Elizabeth Harausz  John Kafuluma Lusiba  Mary Nsereko  John L. Johnson  Zahra Toossi  Sam Ogwang  W. Henry Boom  Moses L. Joloba
Affiliation:aDivision of Infectious Disease and HIV Medicine, Case Western Reserve University, Cleveland, Ohio, USA;bCollege of Health Sciences, Makerere University and Mulago Hospital, Kampala, Uganda;cUganda-CWRU Research Collaboration, Cleveland, Ohio, USA;dDepartment of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
Abstract:The specificities and sensitivities of the Bactec mycobacterial growth indicator tube (MGIT) system for the recovery of Mycobacterium tuberculosis from pleural fluid are not statistically different than those of the Myco/F lytic liquid culture system. The time to positivity is shorter in the MGIT system (12.7 versus 20.7 days, respectively; P = 0.007). The Myco/F lytic culture system may be an alternative to the MGIT system for diagnosing pleural tuberculosis.
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