口服普萘洛尔治疗婴幼儿增殖期血管瘤:英国儿科皮肤病学会共识及临床指南

婴幼儿血管瘤(infantile hemangiomas, IH)是最常见的婴幼儿血管良性肿瘤。关于适应证、诊疗前检查、PHACES综合征的治疗、停药时间等,目前仍存在诸多分歧。本研究使用改进的德尔菲法(Delphi technique),包括国际性治疗方法调查,对已发表文献的系统评价、面对面多学科专家会谈以及匿名投票,就8大类条目共47项指南内容达成共识。本临床指南有助于标准化和简化口服普萘洛尔治疗婴幼儿血管瘤的过程,并且协助临床决策。

Oral propranolol in the treatment of proliferating infantile haemangiomas: British Society for Paediatric Dermatology consensus guidelines (translation version)

Infantile hemangiomas IH are the most common vascular tumors of infancy. However, there are still some controversies over indications, pretreatment investigations, its use in PHACES syndrome as well as cessation of treatment. The present study applied a modified Delphi technique involving an international treatment survey, a systematic evidence review of the literature, a face-to-face multidisciplinary panel meeting and anonymous voting. The expert panel achieved consensus on 47 statements in eight categories eventually. This clinical guideline will contribute to standardize and simplify the treatment of IH with oral propranolol and assist in clinical decision-making.