口腔医疗中恶性高热临床诊治中国专家共识

恶性高热(malignant hyperthermia,MH)是在有易感体质的患者中,由麻醉药或其他因素所诱发而出现的一系列病理生理及临床变化的特定性疾病。该病具有常染色体显性遗传特征,好发于青少年,可伴有唇腭裂等先天性疾病。由于各类麻醉药物在临床医学中的广泛应用,该病越来越受到广大临床医师的重视。MH的治疗手段有其特殊性,误诊和误治可能导致患者死亡等严重后果。制定口腔医学中MH临床诊治中国专家共识的目的,是希望广大口腔临床医师在诊疗过程中警惕MH的发生,减少误诊误治,提高患者的救治成功率。

Chinese expert consensus on diagnosis and clinical management of malignant hyperthermia in oral medicine

Malignant hyperthermia (MH) is an autosomal dominant disease induced by anesthetic drugs or other factors and present a series of pathologic physiology and clinical changes in patients with susceptibility. MH is prone to occur in adolescents, and patients may be accompanied by congenital diseases like cleft lip and palate. Due to the wide application of all kinds of anesthetic drugs in clinical procedures, this disease has attracted more and more attention from clinicians. The treatment of MH has its particularity, misdiagnosis and mistreatment may lead to serious consequences even death. The purpose of formulating the consensus of experts on MH in oral medicine is to hope that the majority of oral clinicians are alert to the occurrence of MH in the process of diagnosis and treatment, reduce misdiagnosis and mistreatment of MH, and improve the treatment success rate of patients.