吲哚氰绿近红外光在微小肝脏占位性病变术中的应用效果

目的:探究吲哚氰绿近红外光在微小肝脏占位性病变术中的应用效果。方法:回顾性分析2015年1月至2016年1月期间我院收治的87例微小肝脏肿瘤患者的临床资料，所有患者均采用肝切除手术治疗，患者术前经CT检查，术中使用吲哚氰绿近红外光技术对肿物进行识别、界定和导航，随访患者术后复发率，分析吲哚氰绿近红外光在微小肝脏占位性病变中的应用效果。结果:87例患者共119个病灶，术前CT检查发现88个病灶，术中通过吲哚氰绿近红外光技术发现103个病灶，两种检查方法均未发现但切开肝脏后暴露发现16个病灶，吲哚氰绿近红外光检查较CT检查能发现更多病灶，差异具有统计学意义（P＜0.05）。CT检查与吲哚氰绿近红外光检查发现的肿瘤平均深度和平均最大直径差异无统计学意义（P＜0.05）。87例患者中16个病灶为全荧光型，23例环形荧光，34例高分化原发性肝癌，31例低分化原发性肝癌。87例患者随访18个月，其中11例患者术后复发，所有患者均为单个肿瘤患者，平均复发时间为（8.93±2.44）个月，复发患者肿瘤距离肝脏表面平均深度为（2.35±0.51）cm，平均大小为（1.61±0.74）cm，所有患者均未进行二次手术，采用以外科治疗的综合治疗。结论:吲哚氰绿近红外光技术对微小肝脏肿瘤的识别率高，病灶显示清晰，在术中具有重要作用。

Application of indocyanine green near-infrared light in tiny liver lesions

Objective:To study the effect of indocyanine green near infrared light in small liver occupying lesions.Methods:The clinical data of 87 patients with small liver tumors admitted in our hospital from January 2015 to January 2016 were analyzed retrospectively.All patients underwent hepatectomy.The patients were examined by CT before operation.Indole cyanide green near-infrared light technique to identify,define and navigate the tumor.Patients with recurrence rate was followed up.Indocyanine green near infrared light in small liver lesions in the application of the effect was analysed.Results:A total of 119 lesions were found in 87 patients.88 lesions were found by preoperative CT examination.103 lesions were found by indocyanine green near-infrared light during surgery.None of the two methods were found but 16 cases were found after incision of liver lesions.Indocyanine green near infrared light examination than CT examination can find more lesions,and the difference was statistically significant (P＜0.05).CT examination and indocyanine green near infrared light examination found that the average depth of tumor and the average maximum diameter difference was not statistically significant (P＜0.05).Of the 87 patients,16 had full fluorescence,23 had circular fluorescence,34 had poorly differentiated primary liver cancer,and 31 had poorly differentiated primary liver cancer.87 patients were followed up for 18 months.Among them,11 patients had recurrence after operation.All patients were single tumor patients with an average recurrence time of (8.93±2.44) months.The mean depth of the tumor was (2.35±0.51) cm,the average size of (1.61±0.74) cm.All patients were not secondary surgery,with the use of surgical treatment of comprehensive treatment.Conclusion:Indocyanine green near infrared light technique has a high recognition rate for small liver tumors,and the lesion is clear and plays an important role in surgery.