No-touch射频消融术治疗小肝癌的安全性和短期疗效

目的:探讨No-touch射频消融术治疗小肝癌患者的安全性和短期疗效。方法:本研究共纳入65例信阳市中心医院小肝癌患者，23例采用No-touch射频消融术治疗，42例采用常规射频消融术（radiofrequency ablation，RFA）治疗。比较和分析治疗并发症和无瘤生存率。结果:两组间基线混杂因素无显著差异。No-touch射频消融术的消融体积显著高于常规射频消融术（P=0.043），但两种技术的剩余肝脏体积和治疗并发症相同（分别为P=0.670和P=1.000）。Kaplan-Meier生存曲线显示:No-touch射频消融组的总体生存率显著高于常规组（P=0.048）。结论:No-touch射频消融术比传统射频消融术具有更高的短期总体生存率，而与传统射频消融术一样安全。

The short-term efficacy and safety of No-touch radiofrequency ablation in treating cirrhosis-based small hepatocellular carcinoma

Objective:To determine the short-term efficacy and safety of No-touch radiofrequency ablation (RFA) in the treatment of small hepatocellular carcinoma (HCC) patients.Methods:A total of 65 patients of small HCC in Xinyang Central Hospital were enrolled in this study,23 cases treated by No-touch RFA and 42 cases by conventional RFA.Treatment complications and overall survival rate were compared and analyzed.Results:There were no significant differences in baseline confounding factors between the two groups.The ablation volume of No-touch RFA technique was significantly higher than conventional RFA (P=0.043),but the remaining liver volume and treatment complications of the two techniques were the same (P=0.670 and P=1.000,respectively).Kaplan-Meier survival showed that the overall survival in No-touch group was significantly higher than conventional group (P=0.048).Conclusion:Our data showed that No-touch RFA provided a higher short-term overall survival rate than conventional RFA,but was as safe as conventional RFA.