| 大分子吸附树脂清除血清中免疫复合物的实验研究 |
| |
| 引用本文： | 于美丽,贾克培,杨彦,郭贤权.大分子吸附树脂清除血清中免疫复合物的实验研究[J].生物医学工程与临床,2000,4(1):24-28. |
| |
| 作者姓名： | 于美丽 贾克培 杨彦 郭贤权 |
| |
| 作者单位： | [1]天津市第三中心医院,天津300170 [2]南开大学分子生物学研究所 [3]南开大学高分子化学研究所 |
| |
| 摘 要： | 目的：采用血液灌流吸附方法清除血液中病理性循环免疫复合物(CIC)，寻找安全有效的吸附剂。方法：从系列亲合吸附剂中筛选出对CIC具有良好吸附性能的AA3吸附剂，测定了该AA3的比表面积、孔容积和平均孔径等参数，分析了吸附剂用量、吸附速率、温度和血中CIC浓度等条件对吸附率、吸附量的影响。结果：AA3可有效地降低血液中CIC的浓度，其吸附率可达40％以上，为治疗多种免疫复合物疾病开辟了一条途径。
|
| 关 键 词： | 循环免疫复合物 AA CIC 血清 治疗 实验研究 附方 途径 方法 目的 |
The Experiment on Macromolecular Absorbent Resin for Removing Serum Immunocomplex |
| |
| Yu Meili,Jia Kepei,Yang Yan, Guo Xianquan Tianjin Third Central Hospital,Tianjin Institute of Polymor Chemistry,Nankai Univesrity,Tianjin Institute for Molecular Biology,Nankai Univesrity,Tianjin.The Experiment on Macromolecular Absorbent Resin for Removing Serum Immunocomplex[J].Biomedical Engineering and Clinical Medicine,2000,4(1):24-28. |
| |
| Authors: | Yu Meili Jia Kepei Yang Yan Guo Xianquan Tianjin Third Central Hospital Tianjin Institute of Polymor Chemistry Nankai Univesrity Tianjin Institute for Molecular Biology Nankai Univesrity Tianjin |
| |
| Institution: | Yu Meili,Jia Kepei,Yang Yan, Guo Xianquan Tianjin Third Central Hospital,Tianjin 300170 Institute of Polymor Chemistry,Nankai Univesrity,Tianjin 300071 Institute for Molecular Biology,Nankai Univesrity,Tianjin 300071 |
| |
| Abstract: | An affinity absorbent( AA3 ) was selected from 5 kinds of absorbent in this paper. The AA3 absorbent was specific absorbent for pathologic circulatory immune complex(CIC) . The physical properties eg. specific surface area, pore volume and average pore diameter of absorbents were determined. The factors affecting the absorption of CIC were discussed. |
| |
| Keywords: | Affinity absorbent Circulatory immune complex Absorption capacity Absorption efficiency |
| 本文献已被 CNKI 维普 等数据库收录！ |
