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Development and validation of a LC method for the enantiomeric purity determination of S-ropivacaine in a pharmaceutical formulation using a recently commercialized cellulose-based chiral stationary phase and polar non-aqueous mobile phase |
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| Authors: | Dossou K S S Chiap P Servais A-C Fillet M Crommen J |
| Affiliation: | Laboratory of Analytical Pharmaceutical Chemistry, Department of Pharmaceutical Sciences, University of Liege, Liège, Belgium. |
| Abstract: | Ropivacaine is the first enantiomerically pure long-acting local anaesthetic used for surgical anaesthesia and post-operative pain relief. |
| Keywords: | Enantiomeric purity Ropivacaine Liquid chromatography Chiral stationary phase Validation |
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