| 宫颈细胞DNA定量分析系统用于宫颈癌筛查的临床意义 |
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| 引用本文： | 钟培根,李末娟.宫颈细胞DNA定量分析系统用于宫颈癌筛查的临床意义[J].中国医药导报,2011,8(27):75-76,78. |
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| 作者姓名： | 钟培根 李末娟 |
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| 作者单位： | 广东医学院第二附属医院妇产科,广东湛江,524000 |
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| 摘 要： | 目的：探讨宫颈细胞DNA定量分析结合液基细胞学诊断方法进行宫颈癌筛查的临床意义。方法：对2009年10月～2010年4月参加我院宫颈癌筛查的5 886例妇女,进行液基细胞学检查和细胞DNA定量分析诊断,在细胞学诊断≥低度鳞状上皮内病变或细胞DNA分析有≥3个异倍体细胞,建议做宫颈病理组织学活检,以病理诊断结果为标准。结果：液基细胞学诊断阳性285例,阳性率为4.84%（285/5 886）;细胞DNA异倍体检出阳性486例,检出率为8.25%（486/5 886）;细胞DNA定量分析结合液基细胞学诊断检出阳性525例,总阳性率为8.92%（525/5 886）。525例患者需做宫颈组织活检,活检结果：阳性375例,阳性率为71.4%（375/525）。结论：细胞DNA定量分析结合液基细胞学诊断方法,能明显提高宫颈癌筛查阳性检出率。
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| 关 键 词： | 细胞DNA定量分析 液基细胞 宫颈癌筛查 |
The clinical significance of quantitative analysis of cervical cellular DNA in cervical cancer screening |
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| ZHONG Peigen,LI Mojuan.The clinical significance of quantitative analysis of cervical cellular DNA in cervical cancer screening[J].China Medical Herald,2011,8(27):75-76,78. |
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| Authors: | ZHONG Peigen LI Mojuan |
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| Institution: | ZHONG Peigen,LI Mojuan Department of Obstetrics and Gynecology,the Second Affiliated Hospital of Guangdong Medical College,Guangdong Province,Zhanjiang 524000,China |
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| Abstract: | Objective: To discuss the clinical significance of quantitative analysis of cellular DNA combined with liquid-based cytology in cervical cancer screening.Methods: 5 886 cases attending cervical cancer screening from October 2009 to April 2010 in our hospital were given quantitative analysis of cellular DNA and liquid-based cytology.The cases whose results exceeding LSIL in cytological diagnosis or exceeding 3 heteroploid cells in quantitative analysis of cellular DNA were suggested to make a biopsy of histo... |
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| Keywords: | Quantitative analysis of cellular DNA Liquid-based cytology Cervical cancer screening |
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