| 经鼻给予布托啡诺对开颅手术麻醉呼气末异氟醚浓度的影响 |
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| 引用本文： | 王云珍,刘文敏,王保国. 经鼻给予布托啡诺对开颅手术麻醉呼气末异氟醚浓度的影响[J]. 中国医药导报, 2011, 8(28): 80-82 |
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| 作者姓名： | 王云珍 刘文敏 王保国 |
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| 作者单位： | 1. 首都医科大学附属北京天坛医院麻醉和疼痛治疗科,北京,100050
2. 首都医科大学第十一临床医学院(北京三博脑科医院)麻醉科,北京,100093 |
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| 摘 要： | 目的：研究麻醉前应用酒石酸布托啡诺鼻喷剂对开颅手术患者术中呼气末异氟醚浓度（PETIso）的影响。方法：采用随机、双盲、对照研究,选择我院择期行开颅手术的患者60例,将其分为布托啡诺组（B组）和生理盐水组（S组）,每组30例。B组给予酒石酸布托啡诺2喷（2 mg）,S组给予生理盐水2喷。麻醉前15 min给药。术中调节异氟醚浓度,维持平均动脉压（MAP）在基础值的（＋10%）～（-20%）范围内。记录手术各个时间点的血压、心率、PETIso及脑电双频指数（BIS）。结果：B组在切皮、钻骨、开骨瓣后的PETIso显著低于S组（P〈0.01）;B组在剪硬膜、颅内操作开始、颅内操作10、20、30 min和缝硬膜的PETIso低于S组（P〈0.05）。结论：麻醉前15 min经鼻给予酒石酸布托啡诺2 mg能有效减少神经外科手术患者开颅期和颅内操作期的PETIso。
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| 关 键 词： | 布托啡诺 镇痛 麻醉 开颅术 经鼻给药 |
The effect of intranasal Butorphanol on the end-tidal pressure of Isoflurane in craniotomy |
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| WANG Yunzhen,LIU Wenmin,WANG Baoguo. The effect of intranasal Butorphanol on the end-tidal pressure of Isoflurane in craniotomy[J]. China Medical Herald, 2011, 8(28): 80-82 |
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| Authors: | WANG Yunzhen LIU Wenmin WANG Baoguo |
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| Affiliation: | WANG Yunzhen1,LIU Wenmin1,WANG Baoguo2 1.Department of Anesthesiology and Pain Management,Beijing Tiantan Hospital Affiliated to Capital Medical University,Beijing 100050,China,2.Department of Anesthesiology,the Eleventh Clinical Medical Institute Affiliated to Capital Medical University(Beijing Sanbo Brain Hospital),Beijing 100093 |
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| Abstract: | Objective: To observe the effect of intranasal Butorphanol on the end-tidal pressure of Isoflurane(PETIso) and the recovery profiles in craniotomy patients.Methods: A randomized,double-blind,parallel study was used.60 patients of our hospital who was undergoing selective craniotomy in this study were selected and divided into Butorphanol group(group B) and normal saline group(group S),group B was given Butorphanol Tartrate Spray in nasal with 2 puffs(2 mg);Group S was given normal saline with 2 puffs.The me... |
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| Keywords: | Butorphanol Analgesia Anesthesia Craniotomy Intranasal |
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