前列地尔对糖尿病肾病蛋白尿的影响

目的评价前列地尔对早期糖尿病肾病患者尿蛋白的影响。方法选择确诊为早期糖尿病肾病患者,随机分为前列地尔组(A组,47例)和对照组(B组,40例)。观察12周,检测各组患者治疗前后尿蛋白等指标。结果 A组治疗后空腹血糖、餐后2 h血糖、血肌酐与对照组比较,差异无统计学意义(P>0.05),但A组治疗后尿蛋白排泄率明显下降,与B组比较,差异有统计学意义(P<0.01)。结论前列地尔可明显降低早期糖尿病肾病患者尿蛋白,从而更大程度地保护肾脏,延缓肾功能恶化。

Alprotadil Influence on Uric Protein due to Diabetic Nephropathy

Objective To evaluate the influence of Alprotadil on uric protein of patients suffering from early-staged diabetic nephropathy.Methods Patients who have been firmly diagnosed as early-staged diabetic nephropathy were chosen and divided into two groups,namely,Alprostadil group(group A) and contrast group(group B).The observation lasted for twelve weeks,and indexes such as uric protein were checked.Results There was no significant difference(P>0.05)between group A and group B in fasting glucose,2h postprandia...