| 瑞替普酶与尿激酶治疗急性ST段抬高型心肌梗死的临床观察 |
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| 引用本文： | 彭丽华.瑞替普酶与尿激酶治疗急性ST段抬高型心肌梗死的临床观察[J].中国医药导报,2011,8(27):55-56. |
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| 作者姓名： | 彭丽华 |
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| 作者单位： | 海南省第二人民医院药剂科,海南五指山,572200 |
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| 摘 要： | 目的：比较瑞替普酶和尿激酶用于急性ST段抬高型心肌梗死患者静脉溶栓治疗的疗效和安全性。方法：88例急性ST段抬高型心肌梗死患者根据静脉溶栓方法的不同分为瑞替普酶组46例,尿激酶组42例,观察和分析两组患者2 h血管再通率、4周内出血率、死亡率及心血管事件发生率。结果：瑞替普酶组和尿激酶组2 h的血管再通率分别为86.96%和73.8%,差异有统计学意义（P〈0.05）。瑞替普酶组溶栓4周内的出血率和死亡率均低于尿激酶组（8.69%、4.35%vs 14.29%、7.14%）,差异有统计学意义（P〈0.05）。结论：瑞替普酶治疗ST段抬高型心肌梗死疗效与安全性优于尿激酶。
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| 关 键 词： | 瑞替普酶 尿激酶 ST段抬高型心肌梗死 溶栓治疗 |
Clinical observation of Reteplase and Urokinase in treatment of acute ST-segment elevation myocardial infarction |
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| PENG Lihua.Clinical observation of Reteplase and Urokinase in treatment of acute ST-segment elevation myocardial infarction[J].China Medical Herald,2011,8(27):55-56. |
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| Authors: | PENG Lihua |
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| Institution: | PENG Lihua Department of Pharmacy,Second People's Hospital of Hainan Province,Wuzhishan 572200,China |
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| Abstract: | Objective: To compare the therapeutic effect and safety of Reteplase and Urokinase in the thrombolytic therapy for the treatment of acute ST-segment elevation myocardial infarction patients.Methods: 88 cases of acute ST-segment elevation myocardial infarction were divided into Reteplase group(46 cases) and Urokinase group(42 cases).2 hours revascularization rate,4 weeks internal bleeding rate,death rate and cardiovascular complications rate of the two groups were observed and analyzed.Results: The 2 hours r... |
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| Keywords: | Reteplase Urokinase ST-segment elevation myocardial infarction Thrombolytic therapy |
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