| 大叶碎米荠水提取液的镇痛抗炎作用研究 |
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| 引用本文： | 刘江舟,向一恒,黄芬,刘凤林,周效思. 大叶碎米荠水提取液的镇痛抗炎作用研究[J]. 中国医药导报, 2011, 8(27): 12-14 |
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| 作者姓名： | 刘江舟 向一恒 黄芬 刘凤林 周效思 |
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| 作者单位： | 邵阳医学高等专科学校,湖南邵阳,422000 |
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| 基金项目： | 2010年度湖南省大学生研究性学习和创新性实验计划资助项目 |
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| 摘 要： | 目的：观察植物大叶碎米荠水提取液的镇痛抗炎作用。方法：以大叶碎米荠为研究对象,采用小鼠热板法、小鼠扭体法观察镇痛作用,采用二甲苯致小鼠耳廓肿胀法、鸡蛋清所致的大鼠足跖肿及毛细血管通透性实验模型观察抗炎作用。结果：大叶碎米荠水提取液能明显延长热板所致的小鼠舔后肢的时间;减少醋酸致小鼠扭体反应的次数;对小鼠耳肿胀及大鼠足肿胀均有显著的抑制作用;降低毛细血管的通透性;显著抑制醋酸所致的小鼠腹腔炎症渗出。结论：大叶碎米荠具有镇痛抗炎作用。
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| 关 键 词： | 大叶碎米荠水提取液 镇痛作用 抗炎作用 |
Study on analgesic and antiinflammatory effects of extract fluid of Cardamine macrophylla Willd. |
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| LIU Jiangzhou,XIANG Yiheng,HUANG Fen,LIU Fenglin,ZHOU Xiaosi. Study on analgesic and antiinflammatory effects of extract fluid of Cardamine macrophylla Willd.[J]. China Medical Herald, 2011, 8(27): 12-14 |
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| Authors: | LIU Jiangzhou XIANG Yiheng HUANG Fen LIU Fenglin ZHOU Xiaosi |
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| Affiliation: | LIU Jiangzhou,XIANG Yiheng,HUANG Fen,LIU Fenglin,ZHOU Xiaosi Shaoyang Medical College,Shaoyang 422000,China |
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| Abstract: | Objective: To evaluate the analgesic and anti-inflammatory effects of extract fluid of Cardamine macrophylla Willd..Methods: The analgesic and anti-inflammatory effects of extract fluid of Cardamine macrophylla Willd.were observed by the hot-plate procedure,mice wringing test,auricula swelling caused by xylene,foot-plate swelling caused by egg white and the experimental model of capillaries permeability of abdominal capillaries in mice induced by acetic acid.Results: It was found that extract fluid of Carda... |
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| Keywords: | Extract fluid of Cardamine macrophylla Willd. Analgesia Anti-inflammation |
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