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| 断端间距对周围神经再生影响的实验研究 | |
| 引用本文： | 张卫国,姜长明,朱继华,张贵源,侯海东. 断端间距对周围神经再生影响的实验研究[J]. 实用手外科杂志, 2001, 15(1): 36-38 |
| 作者姓名： | 张卫国 姜长明 朱继华 张贵源 侯海东 |
| 作者单位： | 1. 大连医科大学附属第一医院骨科, 2. 抚顺市中医院骨科 3. 瓦房店市第五人民医院骨科 |
| 摘 要： | 目的探索较佳修复周围神经损伤的方法.方法以SD大鼠坐骨神经为实验模型,观察神经切断后保留不同间隙修复后的神经再生情况.术后6周、8周处死大鼠,分别行电生理检测、腓肠肌湿重观察、组织学观察及神经轴突计数.结果保留3mm神经断端间隙时,各项检查结果均优于其他各组.结论保留3mm神经断端间隙,术后神经功能恢复最好,可有效地发挥神经再生的趋化作用,且对轴突再生速度无影响. |
| 关 键 词： | 周围神经 再生 小间隙 |
| 修稿时间： | 2000-04-18 |
Experimental study of small gap repair after nerve injury. |
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| ZHANG Weiguo,JIANG Changming,ZHU Jihua,et al.. Experimental study of small gap repair after nerve injury.[J]. Chinese Journal of Practical Hand Surgery, 2001, 15(1): 36-38 | |
| Authors: | ZHANG Weiguo JIANG Changming ZHU Jihua et al. |
| Affiliation: | ZHANG Weiguo,JIANG Changming,ZHU Jihua,et al. Department of Orthopedics,The First Affiliated Hospital of Dalian Medical University,Dalian 116011 |
| Abstract: | Objective To find a better method for repairing peripheral nerves after nerve injury. Methods 48 SD rats were randomly divided into four groups. The sciatic nerve in rats were cut and repaired by silicone chamber with small gap of 0mm, 3mm, 5mm and 7mm. Wet weight of the gastrocnemius, electrophysiologic study, histologic study and morphologic analysis were performed at 6 weeks and 8 weeks after operation. Results There was a significant difference in all of those parameters between 3mm gap group and other three groups at 8 weeks. Conclusion 3mm space is the best gap for sciatic nerve anastomosis in rat after injury. |
| Keywords: | Peripheral nerve Regeneration Small gap |
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