老年心血管疾病患者血糖 尿酸 血脂变化及其与临床相关性分析

目的 探讨老年心血管疾病患者血糖、尿酸、血脂的变化及其与临床的相关性.方法 选取2013年8月至2014年5月确诊的心血管疾病人群,其中冠心病组100例、高血压组100例为疾病组,另选同年龄段的体检人员（排除炎症及心血管疾患）63例为对照组.比较三组人群的血糖（GLU）、血尿酸（URIC）及血脂水平.结果 疾病组除男性冠心病患者URIC水平较对照组明显增高,差异有统计学意义（P＜0.05）外,其他各项结果并无增高.冠心病组男性TC及LDDC水平较高血压组水平低,差异有统计学意义（P＜0.01）;冠心病组女性的TC、HDL-C及LPa水平较高血压组低,差异有统计学意义（P＜0.05）;疾病组TC、LDL-C、HDL-C水平与对照组比较,差异有统计学意义（P＜0.05或0.01）;疾病组TG/TC、LPa/TC的比值较对照组明显增高,差异有统计学意义（P＜0.05）.结论 血糖、尿酸、血脂水平及性别差异与老年心血管疾病存在明显相关性,在诊断和筛查心脑血管疾病、改善预后等方面具有重要的临床意义.

Analysis of changes of blood sugar,uric acid and blood lipids of elderly patients with cardiovascular disease and their correlation with clinic

Objective To investigate the changes of blood sugar, uric acid and blood lipids of elderly patients with cardi- ovascular disease（CVD） and their correlation with clinic.Methods Cases confirmed with CVD from August,2013 to May, 2014 were collected. Among them 100 eases of coronary heart disease and 100 cases of hypertension were selected as disease groups. Meanwhile, people （those who had inflammation and CVD were excluded） at the same age were selected as control group.Then, blood glucose（ GLU）, blood uric acid（ URIC ） and blood lipid levels of the above groups were compared.Results In the disease groups, difference of URIC between groups was statistically significant （P〈0.05） except that of male patients got significantly higher and their other results of indexes did not increase.TC and LDL-C levels of male patients in the coro- nary heart disease group was significantly lower than those of the hypertension group, so the difference was statistically signif- icant（ P〈0. 01 ）.TC, HDL-C and LPa levels of females in the coronary heart disease group were significantly lower than those of the hypertension group,so the difference was statistically significant（ P〈0. 05）.Difference of TC ,LDL-C and HDL-C levels between the disease groups and the control group were statistically significant （P〈0.05 or 0.01 ）.Ratio of TG/TC and LPa/ TC in the disease groups were significantly higher than those of the control group, so the difference was statistically significant （P〈0. 05）.Conclusion GLU, URIC, lipid levels and sex difference have significant correlation with senile cardiovascular disease.They have clinical significance in diagnosing and screening cardio-cerebrovascular diseases, and improving prognosis, etc.