| BSAP MUM1在经典型霍奇金淋巴瘤的表达及意义 |
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| 引用本文： | 郗彦凤,徐恩伟,白文启,王晋芬,孙瑞芳. BSAP MUM1在经典型霍奇金淋巴瘤的表达及意义[J]. 中国药物与临床, 2007, 7(9): 670-671 |
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| 作者姓名： | 郗彦凤 徐恩伟 白文启 王晋芬 孙瑞芳 |
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| 作者单位： | 1. 山西省肿瘤医院病理科,太原,030013
2. 山西省肿瘤医院肛肠科,太原,030013 |
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| 摘 要： | 目的探讨BSAP、MUM1在经典型霍奇金淋巴瘤的表达情况。方法对81例经典型霍奇金淋巴瘤应用免疫组织化学Envision二步法进行BASP、MUM1、BCL-6、CD10、CD3、CD20、CD15、CD30的标记。结果CD3、BCL-6、CD10全部阴性,BASP、MUM1、CD20、CD15、CD30的阳性率分别为58.02%、100%、7.41%、59.26%、100%。结论经典型霍奇金淋巴瘤的H/RS细胞起源于生发中心后期分化的B细胞,它是一种活化的B细胞。
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| 关 键 词： | B淋巴细胞 经典型霍奇金淋巴瘤 H/RS细胞 B细胞特异性激活蛋白 MUM1 |
| 修稿时间： | 2007-05-23 |
The expression and significance of BASP and MUM1 in classical hodgkin lymphoma |
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| XI Yan-feng,XU En-wei,BAI Wen-qi,WANG Jin-fen,SUN Rui-fang. The expression and significance of BASP and MUM1 in classical hodgkin lymphoma[J]. Chinese Remedies & Clinics, 2007, 7(9): 670-671 |
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| Authors: | XI Yan-feng XU En-wei BAI Wen-qi WANG Jin-fen SUN Rui-fang |
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| Abstract: | Objective To investigate the expressions of BSAP and MUM1 in classical Hodgkin′s lymphoma (CHL). Methods The expressions of BSAP, MUM1, CD3, CD20, CD15 and CD30 were assessed with two-step Envision method in 81 patients with CHL. Results In all cases, expressions of CD3, BCL-6 and CD10 were negative, whereas the positive rate of BSAP, MUM1, CD20, CD15 and CD30 were 58.02%, 100%, 7.41%, 59.26% and 100%, respectively. Conclusion The H/RS cells of classical Hodgkin′s lymphoma appear to be derived from a later stage of germinal center B cells, and therefore, are activated B cells. |
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| Keywords: | MUM1 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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