| 针刺“足三里”穴对大鼠血浆、不同脑区及脾脏中环核苷酸含量的影响 |
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| 引用本文： | 方军,宫斌.针刺“足三里”穴对大鼠血浆、不同脑区及脾脏中环核苷酸含量的影响[J].针刺研究,1994,19(1):42-45. |
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| 作者姓名： | 方军 宫斌 |
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| 作者单位： | 上海中医学院核医学研究室!200032(方军，宫斌，莫启忠，匡兴伟，徐多为)，上海中医学院针灸系(李建萍) |
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| 摘 要： | 在针刺“足三里”穴位产生镇痛作用时，观察了大鼠血浆、脑及脾脏组织中环核苷酸的含量变化。以捆绑不针刺大鼠作为对照组，针刺“太冲”穴为针刺对照组。观察到针刺“足三里”穴可使血浆中cAMP含量升高（P＜0．05），脾脏的cAMP含量有升高趋势。大脑皮层中cAMP含量有降低趋势。针刺足三里和太冲后在皮层及脊髓中cAMP、cGMP及cAMP／cGMP的比值有显著的不同。提示针刺“足三里”和“太冲”对cAMP和cGMP含量变化有明显着异。
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| 关 键 词： | 环核苷酸 足三里 血浆 脑 脾脏 |
The Influence of Acupuncture at Zusanli on Cyclic Nucleotide Contents of Plasma,Different Brain Regions and Spleen in Rats |
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| Abstract: | We observed cyclic nucleotide content of plasma, brain and Spleen tissues when analgesia was produced by acupuncture at the Zusanli. The restrained group without acupuncture was as blank control and acupuncture at Taichong as acupuncture control. We found that after acupuncture at Zusanhi the concentration of cyclic nucleotide in plasma was increased significantly(P<0. 05) and the cAMP concentration of spleen had a tendency of enhancement, but the content of cAMP in the cortex had a tendency of decrease. The concentration of cAMP, cGMP and its ratio cAMP/cGMP was different in cortex and spinal cord between acupuncture at Zusanli and Taichong groups. These results showed that acupuncture at Zusanli and Taichong could induce different changes of concentration of cAMP and cGMP |
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