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PANCURONIUM ALLERGY: A CASE REPORT
Authors:PATRIARCA, G.   NUCERA, E.   SCHIAVINO, D.   ROMANO, A.   RIENZO, V. DI   PELLEGRINO, S.   FAIS, G.
Affiliation:Department of Allergology, Catholic University Largo Gemelli, 8 00168 Rome, Italy
Abstract:A case of anaphylactic shock to pancuronium bromide is describedin which a type l immunological reaction occurred. A 33-yr-oldmale anaesthetist, with no family or personal history of allergy,collapsed soon after induction of anaesthesia. The drugs usedincluded fentanyl, droperidol, thiopentone and pancuronium.Diffuse erythema occurred, with probable cardiac arrest. Thepatient was treated with cardiac massage, sympathomimetics andcortisone, and made a complete recovery. Examination (skin tests,passive transfer according to Prausnitz and Küstner, invitro lymphocyte transformation test, total lgE assay) revealedthat the allergic reaction was to pancuronium bromide.
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