早期乳腺癌保乳术后全乳放疗替代模式

全乳房照射已被用于降低早期乳腺癌保乳术后同侧乳腺肿瘤复发的风险,并且多项随机临床试验和荟萃分析已经证明这一放疗模式安全有效,但随着放疗技术的进步以及患者生存期的延长,这种标准治疗模式目前也面临着一些挑战,其替代模式受到了越来越多的关注.其中部分乳腺照射、全乳大分割放疗、省略放疗针对不同的乳腺癌患者,疗效与全乳腺常规照射相当,且降低了不良反应,同时缩短了治疗时程,减轻了患者负担,值得在临床推广应用.

Alternative mode of whole-breast radiotherapy after breast-conserving surgery in early-stage breast cancer

Whole-breast irradiation has been used to reduce the risk of ipsilateral breast tumor recurrence after breast-conserving surgery for early breast cancer.A number of randomized clinical trials and metaanalyses have demonstrated the effectiveness and safety of whole-breast irradiation.With the progress of radiotherapy and the survival extented of patients,this standard treatment model is facing some challenges for different breast cancer groups,and its alternative model has been paid more attention at the same time.The efficacy of partial breast irradiation,hypofactionated whole breast irradiation and the omission of breast RT are equivalent to whole-breast irradiation,while the side effects are reduced.In the same time,they shorten the treatment time of patient and reduce the burden on the patient,which is worth for popularization and application in clinic.