| Dickkopf-1相关肿瘤转移研究进展 |
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| 引用本文： | 朱秋梅,张勇. Dickkopf-1相关肿瘤转移研究进展[J]. 国际肿瘤学杂志, 2017, 44(6). DOI: 10.3760/cma.j.issn.1673-422X.2017.06.010 |
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| 作者姓名： | 朱秋梅 张勇 |
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| 作者单位： | 200062,上海市普陀区中心医院中医肿瘤科 |
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| 基金项目： | National Natural Science Foundation of China (81273733)国家自然科学基金 |
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| 摘 要： | 作为一种分泌型糖蛋白,Dickkopf-1(DKK1)与肿瘤转移关系密切,在肿瘤中高表达或低表达,其异常高表达促进肝癌、胃癌、非小细胞肺癌和乳腺癌等多种恶性肿瘤的转移.最新研究发现,DKK1与肿瘤的潜在转移关系密切.
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| 关 键 词： | 肿瘤转移 治疗 Dickkopf-1 |
Research progress of Dickkopf-1 related tumor metastasis |
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| Zhu Qiumei,Zhang Yong. Research progress of Dickkopf-1 related tumor metastasis[J]. Journal of International Oncology, 2017, 44(6). DOI: 10.3760/cma.j.issn.1673-422X.2017.06.010 |
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| Authors: | Zhu Qiumei Zhang Yong |
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| Abstract: | As a secreted glycoprotein,Dickkopf-1 (DKK1) is closely related to tumor metastasis,and it is highly or lowly expressed in tumor.The high expression of DKK1 promotes the metastasis of a variety of malignant tumors including liver cancer,gastric cancer,non-small cell lung cancer and breast cancer.Recent studies have found that DKK1 is inextricably bound up with the latent metastasis of tumor. |
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| Keywords: | Neoplasm metastasis Therapy Dickkopf-1 |
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