| 微小RNA与卵巢癌 |
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| 引用本文： | 化定超,王新宇.微小RNA与卵巢癌[J].国际肿瘤学杂志,2017,44(8). |
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| 作者姓名： | 化定超 王新宇 |
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| 作者单位： | 1. 浙江大学医学院附属妇产科医院妇瘤科,杭州,310006;2. 浙江大学医学院附属第四医院妇产科 |
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| 摘 要： | 微小RNA (miRNA)的异常表达与卵巢癌的发生发展密切相关,其参与调控卵巢癌的发生、侵袭和转移以及抗癌药物耐药性形成等过程.作为一种重要的生物学标志物,miRNA有望成为卵巢癌早期诊断与预后判断的新靶点,为卵巢癌的治疗提供新的途径.
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| 关 键 词： | 微RNAs 卵巢肿瘤 抗药性 肿瘤 上皮-间质转化 肿瘤浸润 |
MicroRNAs and ovarian cancer |
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| Hua Dingchao,Wang Xinyu.MicroRNAs and ovarian cancer[J].Journal of International Oncology,2017,44(8). |
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| Authors: | Hua Dingchao Wang Xinyu |
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| Abstract: | The abnormal expressions of microRNAs (miRNAs) are closely related to the genesis and development of ovarian cancer.MiRNAs are involved in carcinogenesis and progression,invasion and metastasis as well as drug resistance.As a kind of significant biomarker,miRNAs are expected to be novel targets for the early diagnosis and prognostic evaluation of ovarian cancer,which provide new ways for the therapy of ovarian cancer. |
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| Keywords: | MicroRNAs Ovarian neoplasms Drug resistance neoplasms Epithelial-mesenchymal transition Neoplasm invasiveness |
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