中国糖调节受损患者药物干预效果的比较分析

糖调节受损(IGR,也称糖尿病前期)是2型糖尿病发生的重要阶段,包括空腹血糖受损和糖耐量减低,应及时筛查、调整生活方式,必要时给予药物干预,从而逆转、延缓或控制疾病的发展,减少糖尿病和心脑血管疾病发生的风险.本文以近10年国内相关临床研究为分析重点,归纳和总结了常用口服降糖药及中药对中国IGR患者的干预效果及特点,为IGR患者用药的选择提供指导和借鉴.

Comparative analysis of drug intervention effect on patients with impaired glucose regulation in China

Impaired glucose regulation(IGR,also named prediabetes)is an abnormal condition and important period for dia?betes mellitus. The period includes impaired fasting glucose or/and impaired glucose tolerance. IGR should be screened promptly and be interfered by life style and drugs to recover normal condition,or to delay and control the development of diabetes mellitus for de?creasing the highrisk of diabetes mellitus and cardiovascular disease. The paper reviews the literature about antiglycemic drugs and tra?ditional Chinese medicine interventions for IGR in China in the recent ten years,and summarizes some characters of these drugs to provide some help for prediabetes.