| 新疆阿魏化学成分及药理活性研究进展 |
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| 引用本文： | 黄雅婷,岳丽君,申翔宇,王坤,刘春兰.新疆阿魏化学成分及药理活性研究进展[J].国际药学研究杂志,2017,44(6). |
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| 作者姓名： | 黄雅婷 岳丽君 申翔宇 王坤 刘春兰 |
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| 作者单位： | 1. 中央民族大学生命与环境科学学院, 北京,100081;2. 100081 北京,中央民族大学生命与环境科学学院;100081 北京,中央民族大学北京市食品环境与健康工程技术研究中心 |
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| 基金项目： | 中央民族大学一流大学一流学科建设项目，"111创新引智计划"工程项目，准格尔北部生态保育技术集成与示范项目 |
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| 摘 要： | 新疆阿魏(Ferula sinkiangensis K.M.Shen)是分布在新疆北部的濒危民族植物药,主要含有倍半萜香豆素、含硫化合物、多糖和芳香族类等多种有效化学成分.目前多采用色谱技术建立指纹图谱实现质量控制.原植物药和特征化合物都具有抑菌、杀虫、抗过敏、抗肿瘤等广泛药理作用.本文主要从资源现状、化学成分、指纹图谱和药理活性等方面对国内外新疆阿魏的研究状况进行综述,为其系统化研究、有效质量控制和高效开发利用提供参考.
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| 关 键 词： | 新疆阿魏 资源分布 化学成分 指纹图谱 药理活性 |
Chemical constituents and pharmacological activities of Ferula sinkiangensis K.M. Shen:research advances |
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| HUANG Ya-ting,YUE Li-jun,SHENG Xiang-yu,WANG Kun,LIU Chun-lan.Chemical constituents and pharmacological activities of Ferula sinkiangensis K.M. Shen:research advances[J].Foreign Medical Sciences(Section of Pharmarcy),2017,44(6). |
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| Authors: | HUANG Ya-ting YUE Li-jun SHENG Xiang-yu WANG Kun LIU Chun-lan |
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| Abstract: | Ferula sinkiangensis K.M. Shen is a kind of endangered national plant medicine in the northern of Xinjiang,China. It mainly contains sesquiterpene coumarins,sulfides,polysaccharides,aromatic compounds and other effective chemical constitu-tions;Chromatography is used to build the fingerprint and to control the medicine quality in most cases. Both raw plant medicine and specific compounds possess pharmacologic activities such as antibacterial,insecticidal,anti-allergic,and antitumor properties. The present paper summarizes the resource distribution,chemical constituents,fingerprints and pharmacological activities of F. sinkian-gensis,to provide reference for its systematic research,effective quality control and efficient development and utilization. |
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| Keywords: | Ferula sinkiangensis K M Shen resource distribution chemical constituents fingerprints pharmacological ac-tivities |
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