贵州省1999～2002年残留麻痹的急性弛缓性麻痹病例发病情况分析

目的　为做好急性弛缓性麻痹 (AFP)病例监测 ,巩固无脊髓灰质炎 (脊灰 )成果。方法　对贵州省 1 999～2 0 0 2年 40 3例残留麻痹的AFP病例的流行病学特征、免疫状况和疾病谱进行了分析。结果　 64 3%的病例为 <5岁儿童 ,6～ 8月发病较多 ,未服苗和服苗 <3次的占 34 0 %。引起残留麻痹的疾病 ,格林 巴利综合征占 52 1 % ,6 2 %的病例为临床符合脊灰和诊断不详病例 ,其中 7例怀疑为接触者疫苗相关麻痹型脊灰。结论　为维持无脊灰状态 ,应加强AFP病例监测 ,提高合格粪便标本的采集率和口服脊灰疫苗常规免疫覆盖率

Analysis on the Residual Paralysis of AFP Cases in Guizhou Province During 1999-2002

Objective Strengthening the surveillance for AFP and consolidating the achievements. Methods From 1999-2002 in Guizhou Province,403 residual paralysis of AFP cases were analyzed in the aspects of epidemiological features,immune state and diseases involved. Results The results indicated that 64.3% of the residual paralysis occurred in children under 5 years old,in most of them the disease onset was in June to August,mainly distributed in the west area of Guizhou Province,34% of them were unvaccinated or not full course vaccinated(<3 times).The diseases concerning to the residual paralysis mainly were Guillain-barre syndrome accounting for 52.1%,the clinical conformity cases and the cases undiagnosed clearly accounted for 6.2%, and 7 cases were suspected to be contacts of vaccine-associated paralytic poliomyelitis. Conclusion Strengthening the surveillance quality for AFP cases,coverage rate of routine immunization and colleting rate of adequate stool specimens should be emphaiszed in order to keep the state of polio-free.