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颅内生殖细胞瘤的诊断及综合治疗
引用本文:董伦,浦佩玉,王虎,彭玉平,漆松涛. 颅内生殖细胞瘤的诊断及综合治疗[J]. 中国临床神经外科杂志, 2003, 8(6): 432-434
作者姓名:董伦  浦佩玉  王虎  彭玉平  漆松涛
作者单位:1. 天津医科大学总医院神经外科,天津,300052
2. 中国人民解放军第一军医大学附属南方医院神经外科,广东广州,510515
摘    要:目的 探讨颅内生殖细胞瘤的诊断及综合治疗方法与疗效。方法 本组颅内生殖细胞瘤31例中,29例手术治疗(含1例行脑室—腹腔分流,3例行脑室外引流),2例未手术。此外,29例进行了放疗,8例进行了化疗。结果 临床症状改善27例,无变化4例。随访27例,13例恢复正常工作;8例生活能自理;2例生活需要帮助;2例术后2年复发,经再次手术,症状缓解;死亡2例。结论 颅内生殖细胞瘤手术难以根治,术后正规放疗效果好,对多发性,复发性肿瘤可放疗加化疗。

关 键 词:颅内生殖细胞瘤 诊断 治疗
文章编号:1009-153X(2003)06-0432-03
修稿时间:2002-12-30

Diagnosis and Treatment of Intracranial Germinoma
DONG Lun,WANG Jun,PENG Yu-ping,et al.. Diagnosis and Treatment of Intracranial Germinoma[J]. Chinese Journal of Clinical Neurosurgery, 2003, 8(6): 432-434
Authors:DONG Lun  WANG Jun  PENG Yu-ping  et al.
Affiliation:DONG Lun,WANG Jun,PENG Yu-ping,et al.Department of Neurosurgery,Affiliated General Hospital,Tianjin Medical University,Tianjin300070,China
Abstract:Objective To investigate the clinical characteristics,and diagnosis and treatment methods of intracranial germinoma.Method Of31paients with intracranial germinoma,29were surgically treated(including1receiving ventriculopperitoneal shunt and3extraven-tricular drain)and2did not undergo the surgery.The radiotherapy was performed in29patients and chemotherapy in8.Results Of31patients,27improved in clinical symptoms and4were unchanged.Of27patients followed up,13returned to their work,8could take care of themselves and2not,2underwent reoperation on for the recurrent tumor and2died.Conclusions It is difficult to cure intracranial germinoma thorou-ghly.The radiotherapy can satisfactorily improve patient's prognosis after the operation.The multiple or recurrent tumors should be treated by chemiotherapy after the operation.
Keywords:Intracranial germinoma  Diagnosis  Treatment
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