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Nipah Virus Infection Outbreak with Nosocomial and Corpse-to-Human Transmission,Bangladesh
Authors:Hossain M.S. Sazzad  M. Jahangir Hossain  Emily S. Gurley  Kazi M.H. Ameen  Shahana Parveen  M. Saiful Islam  Labib I. Faruque  Goutam Podder  Sultana S. Banu  Michael K. Lo  Pierre E. Rollin  Paul A. Rota  Peter Daszak  Mahmudur Rahman  Stephen P. Luby
Affiliation:Author affiliations: icddr,b, Dhaka, Bangladesh (H.M.S. Sazzad, M.J. Hossain, E.S. Gurley, S. Parveen, M.S. Islam, L.I. Faruque, G. Podder, S.P. Luby); ;Institute of Epidemiology, Disease Control and Research, Dhaka (K.M.H. Ameen, S.S. Banu, M. Rahman); ;Centers for Disease Control and Prevention, Atlanta, Georgia, USA (M.K. Lo, P.E. Rollin, P.A. Rota, S.P. Luby); ;EcoHealth Alliance, New York, New York, USA (P. Daszak)
Abstract:Active Nipah virus encephalitis surveillance identified an encephalitis cluster and sporadic cases in Faridpur, Bangladesh, in January 2010. We identified 16 case-patients; 14 of these patients died. For 1 case-patient, the only known exposure was hugging a deceased patient with a probable case, while another case-patient’s exposure involved preparing the same corpse for burial by removing oral secretions and anogenital excreta with a cloth and bare hands. Among 7 persons with confirmed sporadic cases, 6 died, including a physician who had physically examined encephalitis patients without gloves or a mask. Nipah virus–infected patients were more likely than community-based controls to report drinking raw date palm sap and to have had physical contact with an encephalitis patient (29% vs. 4%, matched odds ratio undefined). Efforts to prevent transmission should focus on reducing caregivers’ exposure to infected patients’ bodily secretions during care and traditional burial practices.
Keywords:Nipah   encephalitis   outbreak   Nipah virus   NiV   nosocomial   healthcare-associated infection   corpse   Bangladesh   viruses   burial practices   PPE   personal protective equipment   health care workers   transmission
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