In-vitro comparative activity of fluconazole and other antifungal agents against Blastoschizomyces capitatus |
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Authors: | M Venditti B Posteraro G Morace P Martino |
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Affiliation: | Patologia Medica II, Istituto di Clinica Medica VI, Università La Sapienza, Roma, Italy. |
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Abstract: | Blastoschizomyces capitatus represents an emerging fungal pathogen in acute leukemia patients. The susceptibility to amphotericin B, 5-fluorocytosine, ketoconazole and fluconazole of nine clinical isolates was evaluated. A specific medium (high resolution medium) was used for testing fluconazole. This agent and 5-fluorocytosine were at least four- to eight-fold more active than amphotericin B and ketoconazole against all isolates but one. |
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