Foamy virus serotypes 1 and 2 in rhesus monkey tissues |
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Authors: | Thomas C O'Brien Paul Albrecht James E Hannah Nicola M Tauraso Barry Robbins Roy W Trimmer |
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Institution: | (1) Present address: Department of Health, Education, and Welfare, Public Health Service, National Institutes of Health, Division of Biologics Standards, Laboratory of Virology and Rickettsiology, Bethesda, Maryland, USA |
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Abstract: | Summary The isolation and serologic identification by cross neutralization tests showed the presence of simian foamy virus serotypes 1 and 2 in primary rhesus monkey brain, spleen, and kidney cell cultures. The frequency of isolation of foamy viruses from brain and spleen cell cultures was 86% and from kidney cell cultures it was 36%. In primary spleen cell cultures 50% of the foamy virus isolates were type 2. Of the 14 animals from which foamy virus was isolated, only 4 demonstrated serum neutralizing antibody to the homologous serotype. The cytopathology of foamy viruses in the primary cell cultures is described. |
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